Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse

Francis Giles; Srdan Verstovsek; Guillermo Garcia-Manero; Deborah Thomas; Farhad Ravandi; William Wierda; Alessandra Ferrajoli; Steve Kornblau; Elias Jabbour; Jianqin Shan; Susan O'Brien; Maher Albitar; Hagop Kantarjian

doi:10.1111/j.1365-2141.2006.06106.x

Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse

Francis Giles
, Srdan Verstovsek
, Guillermo Garcia-Manero
, Deborah Thomas
, Farhad Ravandi
, William Wierda
, Alessandra Ferrajoli
, Steve Kornblau
, Elias Jabbour
, Jianqin Shan
, Susan O'Brien
, Maher Albitar
, Hagop Kantarjian

The University of Texas Health Science Center at Houston
Department of Cancer Biology

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

19 Citations (Scopus)

Abstract

In order to validate the European Prognostic Index (EPI) for patients ≤60 years with acute myeloid leukaemia in first relapse, a cohort of 599 such patients, treated between 1980 and 2004 at the MD Anderson Cancer Center, were assessed using this prognostic index. Three risk groups were defined: favourable, 76 patients (13%) [Overall survival (OS), 64% at 1 year, 22% at 5 years]; intermediate, 137 patients (23%) (OS, 38% at 1 year, 12% at 5 years); and poor, 386 patients (64%) (OS, 17% at 1 year 6% at 5 years). The EPI is reproducible and useful.

Original language	English
Pages (from-to)	58-60
Number of pages	3
Journal	British Journal of Haematology
Volume	134
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2141.2006.06106.x
Publication status	Published - Jul 2006
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Acute myeloid leukaemia
First relapse
Prognosis

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10.1111/j.1365-2141.2006.06106.x

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Giles, F., Verstovsek, S., Garcia-Manero, G., Thomas, D., Ravandi, F., Wierda, W., Ferrajoli, A., Kornblau, S., Jabbour, E., Shan, J., O'Brien, S., Albitar, M., & Kantarjian, H. (2006). Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse. British Journal of Haematology, 134(1), 58-60. https://doi.org/10.1111/j.1365-2141.2006.06106.x

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title = "Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse",

abstract = "In order to validate the European Prognostic Index (EPI) for patients ≤60 years with acute myeloid leukaemia in first relapse, a cohort of 599 such patients, treated between 1980 and 2004 at the MD Anderson Cancer Center, were assessed using this prognostic index. Three risk groups were defined: favourable, 76 patients (13\%) [Overall survival (OS), 64\% at 1 year, 22\% at 5 years]; intermediate, 137 patients (23\%) (OS, 38\% at 1 year, 12\% at 5 years); and poor, 386 patients (64\%) (OS, 17\% at 1 year 6\% at 5 years). The EPI is reproducible and useful.",

keywords = "Acute myeloid leukaemia, First relapse, Prognosis",

author = "Francis Giles and Srdan Verstovsek and Guillermo Garcia-Manero and Deborah Thomas and Farhad Ravandi and William Wierda and Alessandra Ferrajoli and Steve Kornblau and Elias Jabbour and Jianqin Shan and Susan O'Brien and Maher Albitar and Hagop Kantarjian",

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Giles, F, Verstovsek, S, Garcia-Manero, G, Thomas, D, Ravandi, F, Wierda, W, Ferrajoli, A, Kornblau, S, Jabbour, E, Shan, J, O'Brien, S, Albitar, M & Kantarjian, H 2006, 'Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse', British Journal of Haematology, vol. 134, no. 1, pp. 58-60. https://doi.org/10.1111/j.1365-2141.2006.06106.x

TY - JOUR

T1 - Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse

AU - Giles, Francis

AU - Verstovsek, Srdan

AU - Garcia-Manero, Guillermo

AU - Thomas, Deborah

AU - Ravandi, Farhad

AU - Wierda, William

AU - Ferrajoli, Alessandra

AU - Kornblau, Steve

AU - Jabbour, Elias

AU - Shan, Jianqin

AU - O'Brien, Susan

AU - Albitar, Maher

AU - Kantarjian, Hagop

PY - 2006/7

Y1 - 2006/7

N2 - In order to validate the European Prognostic Index (EPI) for patients ≤60 years with acute myeloid leukaemia in first relapse, a cohort of 599 such patients, treated between 1980 and 2004 at the MD Anderson Cancer Center, were assessed using this prognostic index. Three risk groups were defined: favourable, 76 patients (13%) [Overall survival (OS), 64% at 1 year, 22% at 5 years]; intermediate, 137 patients (23%) (OS, 38% at 1 year, 12% at 5 years); and poor, 386 patients (64%) (OS, 17% at 1 year 6% at 5 years). The EPI is reproducible and useful.

AB - In order to validate the European Prognostic Index (EPI) for patients ≤60 years with acute myeloid leukaemia in first relapse, a cohort of 599 such patients, treated between 1980 and 2004 at the MD Anderson Cancer Center, were assessed using this prognostic index. Three risk groups were defined: favourable, 76 patients (13%) [Overall survival (OS), 64% at 1 year, 22% at 5 years]; intermediate, 137 patients (23%) (OS, 38% at 1 year, 12% at 5 years); and poor, 386 patients (64%) (OS, 17% at 1 year 6% at 5 years). The EPI is reproducible and useful.

KW - Acute myeloid leukaemia

KW - First relapse

KW - Prognosis

UR - https://www.scopus.com/pages/publications/33744803234

U2 - 10.1111/j.1365-2141.2006.06106.x

DO - 10.1111/j.1365-2141.2006.06106.x

M3 - Article

C2 - 16803568

AN - SCOPUS:33744803234

SN - 0007-1048

VL - 134

SP - 58

EP - 60

JO - British Journal of Haematology

JF - British Journal of Haematology

IS - 1

ER -

Validation of the European Prognostic Index for younger adult patients with acute myeloid leukaemia in first relapse

Abstract

UN SDGs

Keywords

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