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Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries

  • Frank J.H. Gijsen
  • , Remko M. Oortman
  • , Jolanda J. Wentzel
  • , Johan C.H. Schuurbiers
  • , Kengo Tanabe
  • , Muzaffer Degertekin
  • , Jurgen M. Ligthart
  • , Attila Thury
  • , Pim J. De Feyter
  • , Patrick W. Serruys
  • , Cornelis J. Slager
  • Erasmus MC

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

87 Citations (Scopus)

Abstract

The true 3-dimensional neointimal thickness distribution in sirolimus-eluting stents was investigated in relation to the shear stress distribution, which was obtained from computational fluid dynamics calculations. Small pits were observed between the stent struts in all patients, and a significant inverse relation between neointimal thickness and shear stress was found, indicating that deeper pits were present in the outside curve of the stented segments.

Original languageEnglish
Pages (from-to)1325-1328
Number of pages4
JournalAmerican Journal of Cardiology
Volume92
Issue number11
DOIs
Publication statusPublished - 1 Dec 2003
Externally publishedYes

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