Use of the bacteriophage-derived endolysin CHAPK-SH3blys as a potent novel treatment for biofilm-associated Staphylococcus aureus wound infections

Hawraa Shahrour; Daniela Alves Ferreira; Deirdre Fitzgerald Hughes; James P O'Gara; Aidan Coffey; Eoghan O'Neill

doi:10.1128/spectrum.00716-25

Use of the bacteriophage-derived endolysin CHAPK-SH3blys as a potent novel treatment for biofilm-associated Staphylococcus aureus wound infections

Hawraa Shahrour
, Daniela Alves Ferreira
, Deirdre Fitzgerald Hughes
, James P O'Gara
, Aidan Coffey
, Eoghan O'Neill

Infectious Disease

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

Original language	English (Ireland)
Pages (from-to)	e00716-25
Journal	Microbiology Spectrum
DOIs	https://doi.org/10.1128/spectrum.00716-25
Publication status	Published - 5 Aug 2025

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10.1128/spectrum.00716-25Licence: CC BY

Cite this

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title = "Use of the bacteriophage-derived endolysin CHAPK-SH3blys as a potent novel treatment for biofilm-associated Staphylococcus aureus wound infections",

author = "Hawraa Shahrour and \{Alves Ferreira\}, Daniela and \{Fitzgerald Hughes\}, Deirdre and O'Gara, \{James P\} and Aidan Coffey and Eoghan O'Neill",

year = "2025",

month = aug,

day = "5",

doi = "10.1128/spectrum.00716-25",

language = "English (Ireland)",

pages = "e00716--25",

journal = "Microbiology Spectrum",

issn = "2165-0497",

publisher = "American Society for Microbiology",

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AU - Shahrour, Hawraa

AU - Alves Ferreira, Daniela

AU - Fitzgerald Hughes, Deirdre

AU - O'Gara, James P

AU - Coffey, Aidan

AU - O'Neill, Eoghan

PY - 2025/8/5

Y1 - 2025/8/5

U2 - 10.1128/spectrum.00716-25

DO - 10.1128/spectrum.00716-25

M3 - Article

SN - 2165-0497

SP - e00716-25

JO - Microbiology Spectrum

JF - Microbiology Spectrum

ER -