Use of piezoelectric shock waves to effect release of amylase from capsules containing the amylase producing rat pancreatic tumour cell line AR42J

B. Jones; U. McCarthy; L. Bunni; L. McHale; M. Butler; J. Seary; A. P. McHale

doi:10.1007/BF01875636

Use of piezoelectric shock waves to effect release of amylase from capsules containing the amylase producing rat pancreatic tumour cell line AR42J

B. Jones, U. McCarthy, L. Bunni, L. McHale, M. Butler, J. Seary, A. P. McHale

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

5 Citations (Scopus)

Abstract

The amylase-producing rat pancreatic tumour cell line AR42J was encapsulated in alginate/poly-L-lysine under conditions where the secreted amylase was retained within the system. On treatment with shock waves from a lithotriptor, the porosity of the capsules was changed and the amylase was released from the system. Conditions of treatment were manipulated in order to maximise release of the amylase without significantly reducing the cell viability.

Original language	English
Pages (from-to)	355-360
Number of pages	6
Journal	Biotechnology Techniques
Volume	3
Issue number	5
DOIs	https://doi.org/10.1007/BF01875636
Publication status	Published - May 1989
Externally published	Yes

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10.1007/BF01875636

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abstract = "The amylase-producing rat pancreatic tumour cell line AR42J was encapsulated in alginate/poly-L-lysine under conditions where the secreted amylase was retained within the system. On treatment with shock waves from a lithotriptor, the porosity of the capsules was changed and the amylase was released from the system. Conditions of treatment were manipulated in order to maximise release of the amylase without significantly reducing the cell viability.",

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AU - Butler, M.

AU - Seary, J.

AU - McHale, A. P.

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AB - The amylase-producing rat pancreatic tumour cell line AR42J was encapsulated in alginate/poly-L-lysine under conditions where the secreted amylase was retained within the system. On treatment with shock waves from a lithotriptor, the porosity of the capsules was changed and the amylase was released from the system. Conditions of treatment were manipulated in order to maximise release of the amylase without significantly reducing the cell viability.

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Use of piezoelectric shock waves to effect release of amylase from capsules containing the amylase producing rat pancreatic tumour cell line AR42J

Abstract

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