Abstract
Randomised trials are a central component of all evidence-informed health care systems and the evidence coming from them helps to support health care users, health professionals and others to make more informed decisions about treatment. The evidence available to trialists to support decisions on design, conduct and reporting of randomised trials is, however, sparse. Trial Forge is an initiative that aims to increase the evidence base for trial decision-making and in doing so, to improve trial efficiency.One way to fill gaps in evidence is to run Studies Within A Trial, or SWATs. This guidance document provides a brief definition of SWATs, an explanation of why they are important and some practical top tips that come from existing experience of doing SWATs. We hope the guidance will be useful to trialists, methodologists, funders, approvals agencies and others in making clear what a SWAT is, as well as what is involved in doing one.
| Original language | English (Ireland) |
|---|---|
| Article number | 139 |
| Journal | Trials |
| Volume | 19 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Feb 2018 |
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Treweek, S,Bevan, S,Bower, P,Campbell, M,Christie, J,Clarke, M,Collett, C,Cotton, S,Devane, D,El Feky, A,Flemyng, E,Galvin, S,Gardner, H,Gillies, K,Jansen, J,Littleford, R,Parker, A,Ramsay, C,Restrup, L,Sullivan, F,Torgerson, D,Tremain, L,Westmore, M,Williamson, PR
- Treweek, S. and Bevan, S. and Bower, P. and Campbell, M. and Christie, J. and Clarke, M. and Collett, C. and Cotton, S. and Devane, D. and El Feky, A. and Flemyng, E. and Galvin, S. and Gardner, H. and Gillies, K. and Jansen, J. and Littleford, R. and Parker, A. and Ramsay, C. and Restrup, L. and Sullivan, F. and Torgerson, D. and Tremain, L. and Westmore, M. and Williamson, P.R.
- Shaun Treweek, Simon Bevan, Peter Bower, Marion Campbell, Jacquie Christie, Mike Clarke, Clive Collett, Seonaidh Cotton, Declan Devane, Adel El Feky, Ella Flemyng, Sandra Galvin, Heidi Gardner, Katie Gillies, Jan Jansen, Roberta Littleford, Adwoa Parker, Craig Ramsay, Lynne Restrup, Frank Sullivan, David Torgerson, Liz Tremain, Matthew Westmore and Paula R. Williamson