Therapeutic cloning: Needs and prospects

Alexander Kind; Alan Colman

doi:10.1006/scdb.1999.0277

Therapeutic cloning: Needs and prospects

Alexander Kind
, Alan Colman

PPL Therapeutics

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

26 Citations (Scopus)

Abstract

There has been widespread speculation regarding the possibility of reprogramming human somatic nuclei by transfer into oocytes. Stem cells derived from such reconstructed embryos could theoretically provide a source of autologous tissue for therapeutic transplantation. However the biological, technical and ethical hurdles which must be overcome before this can be realised are considerable. Here we review the background and prospects for such work.

Original language	English
Pages (from-to)	279-286
Number of pages	8
Journal	Seminars in Cell and Developmental Biology
Volume	10
Issue number	3
DOIs	https://doi.org/10.1006/scdb.1999.0277
Publication status	Published - Jun 1999
Externally published	Yes

Keywords

Embryo
ES cells
Nuclear transfer
Stem cells
Transplantation

Access to Document

10.1006/scdb.1999.0277

Cite this

@article{b30b52d4a5764a668f2c6089a446f3f0,

title = "Therapeutic cloning: Needs and prospects",

abstract = "There has been widespread speculation regarding the possibility of reprogramming human somatic nuclei by transfer into oocytes. Stem cells derived from such reconstructed embryos could theoretically provide a source of autologous tissue for therapeutic transplantation. However the biological, technical and ethical hurdles which must be overcome before this can be realised are considerable. Here we review the background and prospects for such work.",

keywords = "Embryo, ES cells, Nuclear transfer, Stem cells, Transplantation",

author = "Alexander Kind and Alan Colman",

year = "1999",

month = jun,

doi = "10.1006/scdb.1999.0277",

language = "English",

volume = "10",

pages = "279--286",

journal = "Seminars in Cell and Developmental Biology",

issn = "1084-9521",

publisher = "Elsevier Ltd",

number = "3",

}

TY - JOUR

T1 - Therapeutic cloning

T2 - Needs and prospects

AU - Kind, Alexander

AU - Colman, Alan

PY - 1999/6

Y1 - 1999/6

N2 - There has been widespread speculation regarding the possibility of reprogramming human somatic nuclei by transfer into oocytes. Stem cells derived from such reconstructed embryos could theoretically provide a source of autologous tissue for therapeutic transplantation. However the biological, technical and ethical hurdles which must be overcome before this can be realised are considerable. Here we review the background and prospects for such work.

AB - There has been widespread speculation regarding the possibility of reprogramming human somatic nuclei by transfer into oocytes. Stem cells derived from such reconstructed embryos could theoretically provide a source of autologous tissue for therapeutic transplantation. However the biological, technical and ethical hurdles which must be overcome before this can be realised are considerable. Here we review the background and prospects for such work.

KW - Embryo

KW - ES cells

KW - Nuclear transfer

KW - Stem cells

KW - Transplantation

UR - https://www.scopus.com/pages/publications/0033142804

U2 - 10.1006/scdb.1999.0277

DO - 10.1006/scdb.1999.0277

M3 - Article

C2 - 10441540

AN - SCOPUS:0033142804

SN - 1084-9521

VL - 10

SP - 279

EP - 286

JO - Seminars in Cell and Developmental Biology

JF - Seminars in Cell and Developmental Biology

IS - 3

ER -

Therapeutic cloning: Needs and prospects

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this