The structure of the lipid anchor of Campylobacter jejuni polysaccharide

Adrian T. Corcoran, Heidi Annuk, Anthony P. Moran

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

18 Citations (Scopus)

Abstract

Campylobacter jejuni is a leading cause of gastroenteritis in humans. Campylobacter jejuni produces extracellular polysaccharides that have been characterized structurally and shown to be independent of lipopolysaccharides. Furthermore, it has been suggested that these C. jejuni polysaccharides are capsular in nature, although their lipid anchor has not been identified. In this report, the occurrence of a lipid-linked capsular-like polysaccharide in C. jejuni is conclusively shown, and the lipid anchor identified as dipalmitoyl-glycerophosphate.

Original languageEnglish
Pages (from-to)228-235
Number of pages8
JournalFEMS Microbiology Letters
Volume257
Issue number2
DOIs
Publication statusPublished - Apr 2006

Keywords

  • Campylobacter jejuni
  • Lipid anchor
  • Polysaccharide

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