The reverse of polymer degradation: In situ crosslinked gel formation through disulfide cleavage

Aram O. Saeed; Ben Newland; Abhay Pandit; Wenxin Wang

doi:10.1039/c1cc16538k

The reverse of polymer degradation: In situ crosslinked gel formation through disulfide cleavage

Aram O. Saeed
, Ben Newland
, Abhay Pandit
, Wenxin Wang

University of Galway

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

20 Citations (Scopus)

Abstract

In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.

Original language	English
Pages (from-to)	585-587
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	4
DOIs	https://doi.org/10.1039/c1cc16538k
Publication status	Published - 14 Dec 2012
Externally published	Yes

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title = "The reverse of polymer degradation: In situ crosslinked gel formation through disulfide cleavage",

abstract = "In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.",

author = "Saeed, \{Aram O.\} and Ben Newland and Abhay Pandit and Wenxin Wang",

year = "2012",

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doi = "10.1039/c1cc16538k",

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journal = "Chemical Communications",

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T2 - In situ crosslinked gel formation through disulfide cleavage

AU - Saeed, Aram O.

AU - Newland, Ben

AU - Pandit, Abhay

AU - Wang, Wenxin

PY - 2012/12/14

Y1 - 2012/12/14

N2 - In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.

AB - In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.

UR - https://www.scopus.com/pages/publications/83455186559

U2 - 10.1039/c1cc16538k

DO - 10.1039/c1cc16538k

M3 - Article

SN - 1359-7345

VL - 48

SP - 585

EP - 587

JO - Chemical Communications

JF - Chemical Communications

IS - 4

ER -

The reverse of polymer degradation: In situ crosslinked gel formation through disulfide cleavage

Abstract

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