Abstract
As the population ages and the life expectancy
increases, tendon injuries will become more prevalent, especially among young
individuals with long life ahead of them. Advancements in engineering,
chemistry and biology have made available an array of three-dimensional
scaffold-based intervention strategies, natural or synthetic in origin.
Further, functionalisation strategies, based on biophysical, biochemical and
biological cues, offer control over cellular functions; localisation and
sustained release of therapeutics biologics; and the ability to positively
interact with the host to promote repair and regeneration. Herein, we
critically discuss current therapies and emerging technologies that aim to
transform tendon treatments in the years to come.
| Original language | English (Ireland) |
|---|---|
| Journal | Advanced Drug Delivery Reviews |
| Publication status | Published - 1 Jan 2014 |
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Lomas, A. J. Ryan, C. N. Sorushanova, A. Shologu, N. Sideri, A. I. Tsioli, V. Fthenakis, G. C. Tzora, A. Skoufos, I. Quinlan, L. R. O'Laighin, G. Mullen, A. M. Kelly, J. L. Kearns, S. Biggs, M. Pandit, A. Zeugolis, D. I.