The future of BRS in bifurcations

Robin P. Kraak; Maik J. Grundeken; Yoshinobu Onuma; Shengxian Tu; Joanna J. Wykrzykowska; Bernard Chevalier; John Ormiston; Patrick W. Serruys

doi:10.4244/EIJV11SVA45

The future of BRS in bifurcations

Robin P. Kraak, Maik J. Grundeken, Yoshinobu Onuma, Shengxian Tu, Joanna J. Wykrzykowska, Bernard Chevalier, John Ormiston, Patrick W. Serruys

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

10 Citations (Scopus)

Abstract

Bioresorbable scaffolds (BRS) provide a new tool for percutaneous treatment of coronary stenosis. Initially, relatively simple coronary artery lesions were treated with this novel technology; nowadays, we have gained more experience with a wide variety of lesions, including bifurcation lesions. Data are limited in terms of the use of BRS in coronary bifurcation lesions, although it has been demonstrated that over time the bioresorbable struts are replaced by a tissue bridge resembling a "neo-carina". Furthermore, data are emerging about the endothelial shear stress (ESS) alterations and blood flow patterns after scaffold implantation. It is likely that ESS and blood flow determinations will guide correct future bifurcation techniques. In the future, BRS with thinner struts and more resistant to fracture are likely to improve bifurcation treatment with BRS.

Original language	English
Pages (from-to)	V188-V192
Journal	EuroIntervention
Volume	11
DOIs	https://doi.org/10.4244/EIJV11SVA45
Publication status	Published - 1 May 2015
Externally published	Yes

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title = "The future of BRS in bifurcations",

abstract = "Bioresorbable scaffolds (BRS) provide a new tool for percutaneous treatment of coronary stenosis. Initially, relatively simple coronary artery lesions were treated with this novel technology; nowadays, we have gained more experience with a wide variety of lesions, including bifurcation lesions. Data are limited in terms of the use of BRS in coronary bifurcation lesions, although it has been demonstrated that over time the bioresorbable struts are replaced by a tissue bridge resembling a {"}neo-carina{"}. Furthermore, data are emerging about the endothelial shear stress (ESS) alterations and blood flow patterns after scaffold implantation. It is likely that ESS and blood flow determinations will guide correct future bifurcation techniques. In the future, BRS with thinner struts and more resistant to fracture are likely to improve bifurcation treatment with BRS.",

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AU - Kraak, Robin P.

AU - Grundeken, Maik J.

AU - Onuma, Yoshinobu

AU - Tu, Shengxian

AU - Wykrzykowska, Joanna J.

AU - Chevalier, Bernard

AU - Ormiston, John

AU - Serruys, Patrick W.

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Bioresorbable scaffolds (BRS) provide a new tool for percutaneous treatment of coronary stenosis. Initially, relatively simple coronary artery lesions were treated with this novel technology; nowadays, we have gained more experience with a wide variety of lesions, including bifurcation lesions. Data are limited in terms of the use of BRS in coronary bifurcation lesions, although it has been demonstrated that over time the bioresorbable struts are replaced by a tissue bridge resembling a "neo-carina". Furthermore, data are emerging about the endothelial shear stress (ESS) alterations and blood flow patterns after scaffold implantation. It is likely that ESS and blood flow determinations will guide correct future bifurcation techniques. In the future, BRS with thinner struts and more resistant to fracture are likely to improve bifurcation treatment with BRS.

AB - Bioresorbable scaffolds (BRS) provide a new tool for percutaneous treatment of coronary stenosis. Initially, relatively simple coronary artery lesions were treated with this novel technology; nowadays, we have gained more experience with a wide variety of lesions, including bifurcation lesions. Data are limited in terms of the use of BRS in coronary bifurcation lesions, although it has been demonstrated that over time the bioresorbable struts are replaced by a tissue bridge resembling a "neo-carina". Furthermore, data are emerging about the endothelial shear stress (ESS) alterations and blood flow patterns after scaffold implantation. It is likely that ESS and blood flow determinations will guide correct future bifurcation techniques. In the future, BRS with thinner struts and more resistant to fracture are likely to improve bifurcation treatment with BRS.

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DO - 10.4244/EIJV11SVA45

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SN - 1774-024X

VL - 11

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The future of BRS in bifurcations

Abstract

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