The crystal structure of a cyclic glycolipid reveals a carbohydrate- carbohydrate interaction interface

Paul V. Murphy, Helge Müller-Bunz, Trinidad Velasco-Torrijos

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

13 Citations (Scopus)

Abstract

The crystal structure of an amphiphilic macrocycle [Velasco-Torrijos, T.; Murphy, P. V., Tetrahedron: Asymmetry 2005, 16, 261-272] derived from saccharides shows extensive hydrogen-bonding networks, including participation of water, that may have relevance for the modelling of carbohydrate-carbohydrate recognition at cell-cell interfaces. The structure may provide a basis for understanding the binding of the macrocycle to hydrophobic probes.

Original languageEnglish
Pages (from-to)1437-1440
Number of pages4
JournalCarbohydrate Research
Volume340
Issue number7
DOIs
Publication statusPublished - 23 May 2005
Externally publishedYes

Keywords

  • Crystal structure
  • Glycolipid
  • Hydrogen bonding
  • Hydrophobic interaction
  • Macrocycle

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