Templated dynamic synthesis of a [3]catenane

Fabien B.L. Cougnon; Nicholas A. Jenkins; G. Dan Pantoş; Jeremy K.M. Sanders

doi:10.1002/anie.201106885

Templated dynamic synthesis of a [3]catenane

Fabien B.L. Cougnon, Nicholas A. Jenkins, G. Dan Pantoş, Jeremy K.M. Sanders

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

101 Citations (Scopus)

Abstract

Three rings: The self-assembly of a water-soluble [3]catenane from a library composed of two linear building blocks, both terminated by cysteine components, is promoted either by a high salt concentration or by the presence of spermine. The spermine-templated synthesis of the [3]catenane shows that such structures can exhibit strong binding interactions with a biologically relevant target in water under near-physiological conditions.

Original language	English
Pages (from-to)	1443-1447
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	6
DOIs	https://doi.org/10.1002/anie.201106885
Publication status	Published - 6 Feb 2012
Externally published	Yes

Keywords

catenanes
molecular recognition
self-assembly
supramolecular chemistry
template synthesis

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10.1002/anie.201106885

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Templated dynamic synthesis of a [3]catenane

Abstract

Keywords

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