Synthesis of alpha-galactosyl ceramide analogues with an a-triazole at the anomeric carbon

Paul Murphy

doi:http://hdl.handle.net/10379/5664

Synthesis of alpha-galactosyl ceramide analogues with an a-triazole at the anomeric carbon

Paul Murphy

Infectious Disease

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

Abstract

synthesis of 1,2,3-triazole containing analogues of a-GalCer and galacturonic acid containing Sphingomonous cell wall antigens is described. Anomerisation was used to provide the required cc-glycosyl azide precursor. Copper azide alkyne cydoaddition (CuAAC) generated the a-triazole linkage. (c) 2014 Elsevier Ltd. All rights reserved.

Original language	English (Ireland)
Number of pages	6
Journal	Tetrahedron
Volume	70
DOIs	https://doi.org/http://hdl.handle.net/10379/5664
Publication status	Published - 1 May 2014

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Authors
McDonagh, AW,Murphy, PV

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abstract = "synthesis of 1,2,3-triazole containing analogues of a-GalCer and galacturonic acid containing Sphingomonous cell wall antigens is described. Anomerisation was used to provide the required cc-glycosyl azide precursor. Copper azide alkyne cydoaddition (CuAAC) generated the a-triazole linkage. (c) 2014 Elsevier Ltd. All rights reserved.",

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AB - synthesis of 1,2,3-triazole containing analogues of a-GalCer and galacturonic acid containing Sphingomonous cell wall antigens is described. Anomerisation was used to provide the required cc-glycosyl azide precursor. Copper azide alkyne cydoaddition (CuAAC) generated the a-triazole linkage. (c) 2014 Elsevier Ltd. All rights reserved.

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DO - http://hdl.handle.net/10379/5664

M3 - Article

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JO - Tetrahedron

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ER -

Synthesis of alpha-galactosyl ceramide analogues with an a-triazole at the anomeric carbon

Abstract

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