Synthesis of (±)-17-methylcamptothecins

Olivier P. Thomas; Cécile Dumas; Anne Zaparucha; Henri Philippe Husson

doi:10.1002/ejoc.200300565

Synthesis of (±)-17-methylcamptothecins

Olivier P. Thomas
, Cécile Dumas
, Anne Zaparucha
, Henri Philippe Husson

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

8 Citations (Scopus)

Abstract

(±)-17-Methylcamptothecins (29) were synthesized from the heteroyohimbane ajmalicine (5) through sequential oxidation steps and E-ring functionalization.

Original language	English
Pages (from-to)	1128-1135
Number of pages	8
Journal	European Journal of Organic Chemistry
Issue number	5
DOIs	https://doi.org/10.1002/ejoc.200300565
Publication status	Published - 27 Feb 2004
Externally published	Yes

Keywords

Ajmalicine
Alkaloids
Antitumor agents
Nitrogen heterocycles
Oxidations

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10.1002/ejoc.200300565

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@article{5517f79a5a984011af36b7456defbf3f,

title = "Synthesis of (±)-17-methylcamptothecins",

abstract = "(±)-17-Methylcamptothecins (29) were synthesized from the heteroyohimbane ajmalicine (5) through sequential oxidation steps and E-ring functionalization.",

keywords = "Ajmalicine, Alkaloids, Antitumor agents, Nitrogen heterocycles, Oxidations",

author = "Thomas, \{Olivier P.\} and C{\'e}cile Dumas and Anne Zaparucha and Husson, \{Henri Philippe\}",

year = "2004",

month = feb,

day = "27",

doi = "10.1002/ejoc.200300565",

language = "English",

pages = "1128--1135",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley-VCH Verlag",

number = "5",

}

TY - JOUR

T1 - Synthesis of (±)-17-methylcamptothecins

AU - Thomas, Olivier P.

AU - Dumas, Cécile

AU - Zaparucha, Anne

AU - Husson, Henri Philippe

PY - 2004/2/27

Y1 - 2004/2/27

N2 - (±)-17-Methylcamptothecins (29) were synthesized from the heteroyohimbane ajmalicine (5) through sequential oxidation steps and E-ring functionalization.

AB - (±)-17-Methylcamptothecins (29) were synthesized from the heteroyohimbane ajmalicine (5) through sequential oxidation steps and E-ring functionalization.

KW - Ajmalicine

KW - Alkaloids

KW - Antitumor agents

KW - Nitrogen heterocycles

KW - Oxidations

UR - https://www.scopus.com/pages/publications/4544384694

U2 - 10.1002/ejoc.200300565

DO - 10.1002/ejoc.200300565

M3 - Article

AN - SCOPUS:4544384694

SN - 1434-193X

SP - 1128

EP - 1135

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 5

ER -

Synthesis of (±)-17-methylcamptothecins

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Keywords

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