Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization

L. G. Bach; M. R. Islam; T. B. Mai; T. T. Nga; L. Niranjanmurthi; K. T. Lim

Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization

L. G. Bach
, M. R. Islam
, T. B. Mai
, T. T. Nga
, L. Niranjanmurthi
, K. T. Lim

Pukyong National University

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

Abstract

A bionanocomposite of poly(2-hydroxyethyl methacrylate) (PHEMA) and hydroxyapatite nanocrystals (HAP NCs) was successfully synthesized via surface thiol-lactam initiated radical polymerization (TLIRP) employing grafting from protocol. The surface chemistry, structure, morphology, and size distribution of PHEMA-g-HAP nanocomposites were exclusively investigated by FT-IR, ¹H-NMR, GPC, XPS, TGA, XRD, SEM, TEM, and DLS analyses. Covalently formed PHEMA-g-HAP nanocomposites demonstrated an exceptionally good dispersibility in both aqueous and organic solvents. A protein immobilization and release study suggested that the synthesized PHEMA-g-HAP nanocomposites possessed a great affinity towards the Bovine Serum Albumin (BSA) protein.

Original language	English
Title of host publication	ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials
Publisher	European Conference on Composite Materials, ECCM
ISBN (Print)	9788888785332
Publication status	Published - 2012
Externally published	Yes
Event	15th European Conference on Composite Materials: Composites at Venice, ECCM 2012 - Venice, Italy Duration: 24 Jun 2012 → 28 Jun 2012

Publication series

Name	ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials

Conference

Conference	15th European Conference on Composite Materials: Composites at Venice, ECCM 2012
Country/Territory	Italy
City	Venice
Period	24/06/12 → 28/06/12

Keywords

Hydroxyapatite
Poly(2-hydroxyethyl methacrylate)
Protein loading
Surface initiated radical polymerization

Cite this

Bach, L. G., Islam, M. R., Mai, T. B., Nga, T. T., Niranjanmurthi, L., & Lim, K. T. (2012). Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization. In ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials (ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials). European Conference on Composite Materials, ECCM.

Bach, L. G. ; Islam, M. R. ; Mai, T. B. et al. / Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization. ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials. European Conference on Composite Materials, ECCM, 2012. (ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials).

@inproceedings{a67ba33d343148fd8153e96691440116,

title = "Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization",

abstract = "A bionanocomposite of poly(2-hydroxyethyl methacrylate) (PHEMA) and hydroxyapatite nanocrystals (HAP NCs) was successfully synthesized via surface thiol-lactam initiated radical polymerization (TLIRP) employing grafting from protocol. The surface chemistry, structure, morphology, and size distribution of PHEMA-g-HAP nanocomposites were exclusively investigated by FT-IR, 1H-NMR, GPC, XPS, TGA, XRD, SEM, TEM, and DLS analyses. Covalently formed PHEMA-g-HAP nanocomposites demonstrated an exceptionally good dispersibility in both aqueous and organic solvents. A protein immobilization and release study suggested that the synthesized PHEMA-g-HAP nanocomposites possessed a great affinity towards the Bovine Serum Albumin (BSA) protein.",

keywords = "Hydroxyapatite, Poly(2-hydroxyethyl methacrylate), Protein loading, Surface initiated radical polymerization",

author = "Bach, \{L. G.\} and Islam, \{M. R.\} and Mai, \{T. B.\} and Nga, \{T. T.\} and L. Niranjanmurthi and Lim, \{K. T.\}",

year = "2012",

language = "English",

isbn = "9788888785332",

series = "ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials",

publisher = "European Conference on Composite Materials, ECCM",

booktitle = "ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials",

note = "15th European Conference on Composite Materials: Composites at Venice, ECCM 2012 ; Conference date: 24-06-2012 Through 28-06-2012",

}

Bach, LG, Islam, MR, Mai, TB, Nga, TT, Niranjanmurthi, L & Lim, KT 2012, Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization. in ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials. ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials, European Conference on Composite Materials, ECCM, 15th European Conference on Composite Materials: Composites at Venice, ECCM 2012, Venice, Italy, 24/06/12.

Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization. / Bach, L. G.; Islam, M. R.; Mai, T. B. et al.
ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials. European Conference on Composite Materials, ECCM, 2012. (ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials).

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

TY - GEN

T1 - Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization

AU - Bach, L. G.

AU - Islam, M. R.

AU - Mai, T. B.

AU - Nga, T. T.

AU - Niranjanmurthi, L.

AU - Lim, K. T.

PY - 2012

Y1 - 2012

N2 - A bionanocomposite of poly(2-hydroxyethyl methacrylate) (PHEMA) and hydroxyapatite nanocrystals (HAP NCs) was successfully synthesized via surface thiol-lactam initiated radical polymerization (TLIRP) employing grafting from protocol. The surface chemistry, structure, morphology, and size distribution of PHEMA-g-HAP nanocomposites were exclusively investigated by FT-IR, 1H-NMR, GPC, XPS, TGA, XRD, SEM, TEM, and DLS analyses. Covalently formed PHEMA-g-HAP nanocomposites demonstrated an exceptionally good dispersibility in both aqueous and organic solvents. A protein immobilization and release study suggested that the synthesized PHEMA-g-HAP nanocomposites possessed a great affinity towards the Bovine Serum Albumin (BSA) protein.

AB - A bionanocomposite of poly(2-hydroxyethyl methacrylate) (PHEMA) and hydroxyapatite nanocrystals (HAP NCs) was successfully synthesized via surface thiol-lactam initiated radical polymerization (TLIRP) employing grafting from protocol. The surface chemistry, structure, morphology, and size distribution of PHEMA-g-HAP nanocomposites were exclusively investigated by FT-IR, 1H-NMR, GPC, XPS, TGA, XRD, SEM, TEM, and DLS analyses. Covalently formed PHEMA-g-HAP nanocomposites demonstrated an exceptionally good dispersibility in both aqueous and organic solvents. A protein immobilization and release study suggested that the synthesized PHEMA-g-HAP nanocomposites possessed a great affinity towards the Bovine Serum Albumin (BSA) protein.

KW - Hydroxyapatite

KW - Poly(2-hydroxyethyl methacrylate)

KW - Protein loading

KW - Surface initiated radical polymerization

UR - https://www.scopus.com/pages/publications/84903973737

M3 - Conference Publication

AN - SCOPUS:84903973737

SN - 9788888785332

T3 - ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials

BT - ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials

PB - European Conference on Composite Materials, ECCM

T2 - 15th European Conference on Composite Materials: Composites at Venice, ECCM 2012

Y2 - 24 June 2012 through 28 June 2012

ER -

Bach LG, Islam MR, Mai TB, Nga TT, Niranjanmurthi L, Lim KT. Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization. In ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials. European Conference on Composite Materials, ECCM. 2012. (ECCM 2012 - Composites at Venice, Proceedings of the 15th European Conference on Composite Materials).

Synthesis, characterization, and protein immobilization study of PHEMA grafted hydroxyapatite nanocrystals via surface initiated radical polymerization

Abstract

Publication series

Conference

Keywords

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