Synthesis and antispasmodic activity of nature identical substituted indanes and analogues

H. Sheridan; S. Lemon; N. Frankish; P. McArdle; T. Higgins; JP James; P. Bhandari

doi:10.1016/0223-5234(90)90185-6

Synthesis and antispasmodic activity of nature identical substituted indanes and analogues

H. Sheridan, S. Lemon, N. Frankish, P. McArdle, T. Higgins, JP James, P. Bhandari

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

33 Citations (Scopus)

Abstract

The synthesis of a series of substituted indanes which provide routes to nature-identical compounds and their analogues is reported. The smooth muscle relaxant activity of a series of substituted indanes and indanones together with their analogues has been measured. A compound with significant smooth muscle relaxant activity has been identified.

Original language	English
Pages (from-to)	603-608
Number of pages	6
Journal	European Journal of Medicinal Chemistry
Volume	25
Issue number	7
DOIs	https://doi.org/10.1016/0223-5234(90)90185-6
Publication status	Published - Sep 1990
Externally published	Yes

Keywords

indanes
indanones
pterosins
smooth muscle relaxant activity

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10.1016/0223-5234(90)90185-6

Cite this

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title = "Synthesis and antispasmodic activity of nature identical substituted indanes and analogues",

abstract = "The synthesis of a series of substituted indanes which provide routes to nature-identical compounds and their analogues is reported. The smooth muscle relaxant activity of a series of substituted indanes and indanones together with their analogues has been measured. A compound with significant smooth muscle relaxant activity has been identified.",

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author = "H. Sheridan and S. Lemon and N. Frankish and P. McArdle and T. Higgins and JP James and P. Bhandari",

year = "1990",

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AU - Sheridan, H.

AU - Lemon, S.

AU - Frankish, N.

AU - McArdle, P.

AU - Higgins, T.

AU - James, JP

AU - Bhandari, P.

PY - 1990/9

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N2 - The synthesis of a series of substituted indanes which provide routes to nature-identical compounds and their analogues is reported. The smooth muscle relaxant activity of a series of substituted indanes and indanones together with their analogues has been measured. A compound with significant smooth muscle relaxant activity has been identified.

AB - The synthesis of a series of substituted indanes which provide routes to nature-identical compounds and their analogues is reported. The smooth muscle relaxant activity of a series of substituted indanes and indanones together with their analogues has been measured. A compound with significant smooth muscle relaxant activity has been identified.

KW - indanes

KW - indanones

KW - pterosins

KW - smooth muscle relaxant activity

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U2 - 10.1016/0223-5234(90)90185-6

DO - 10.1016/0223-5234(90)90185-6

M3 - Article

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EP - 608

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

IS - 7

ER -

Synthesis and antispasmodic activity of nature identical substituted indanes and analogues

Abstract

Keywords

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