Structural investigation of the capsular polysaccharide of Klebsiella serotype k23

Guy G.S. Dutton; Keith L. Mackie; Angela V. Savage; Mary D. Stephenson

doi:10.1016/S0008-6215(00)83245-0

Structural investigation of the capsular polysaccharide of Klebsiella serotype k23

Guy G.S. Dutton
, Keith L. Mackie
, Angela V. Savage
, Mary D. Stephenson

University of British Columbia

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

30 Citations (Scopus)

Abstract

Klebsiella K23 capsular polysaccharide has been investigated by the techniques of hydrolysis, methylation, Smith degradation-periodate oxidation, and base-catalysed degradation, either on the original or the carboxyl-reduced polysaccharide. The structure was found to consist of a tetrasaccharide repeating-unit, as shown below. The anomeric configurations of the sugar residues were determined by ₁H-and ¹³C-n.m.r. spectroscopy on the original and degraded polysaccharides.{A figure is presented}.

Original language	English
Pages (from-to)	125-131
Number of pages	7
Journal	Carbohydrate Research
Volume	66
Issue number	1
DOIs	https://doi.org/10.1016/S0008-6215(00)83245-0
Publication status	Published - Oct 1978
Externally published	Yes

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title = "Structural investigation of the capsular polysaccharide of Klebsiella serotype k23",

abstract = "Klebsiella K23 capsular polysaccharide has been investigated by the techniques of hydrolysis, methylation, Smith degradation-periodate oxidation, and base-catalysed degradation, either on the original or the carboxyl-reduced polysaccharide. The structure was found to consist of a tetrasaccharide repeating-unit, as shown below. The anomeric configurations of the sugar residues were determined by 1H-and 13C-n.m.r. spectroscopy on the original and degraded polysaccharides.\{A figure is presented\}.",

author = "Dutton, \{Guy G.S.\} and Mackie, \{Keith L.\} and Savage, \{Angela V.\} and Stephenson, \{Mary D.\}",

year = "1978",

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AU - Dutton, Guy G.S.

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AU - Savage, Angela V.

AU - Stephenson, Mary D.

PY - 1978/10

Y1 - 1978/10

N2 - Klebsiella K23 capsular polysaccharide has been investigated by the techniques of hydrolysis, methylation, Smith degradation-periodate oxidation, and base-catalysed degradation, either on the original or the carboxyl-reduced polysaccharide. The structure was found to consist of a tetrasaccharide repeating-unit, as shown below. The anomeric configurations of the sugar residues were determined by 1H-and 13C-n.m.r. spectroscopy on the original and degraded polysaccharides.{A figure is presented}.

AB - Klebsiella K23 capsular polysaccharide has been investigated by the techniques of hydrolysis, methylation, Smith degradation-periodate oxidation, and base-catalysed degradation, either on the original or the carboxyl-reduced polysaccharide. The structure was found to consist of a tetrasaccharide repeating-unit, as shown below. The anomeric configurations of the sugar residues were determined by 1H-and 13C-n.m.r. spectroscopy on the original and degraded polysaccharides.{A figure is presented}.

UR - https://www.scopus.com/pages/publications/49349124689

U2 - 10.1016/S0008-6215(00)83245-0

DO - 10.1016/S0008-6215(00)83245-0

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SN - 0008-6215

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ER -

Structural investigation of the capsular polysaccharide of Klebsiella serotype k23

Abstract

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