Stereochemical Study of Puna'auic Acid, an Allenic Fatty Acid from the Eastern Indo-Pacific Cyanobacterium Pseudanabaena sp

Emmanuel Roulland, Hiren Solanki, Kevin Calabro, Mayalen Zubia, Grégory Genta-Jouve, Olivier P. Thomas

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

17 Citations (Scopus)

Abstract

The isolation and structure elucidation of puna'auic acid, an allenic fatty acid isolated from a marine cyanobacterium, is described. All configurations were first assessed through molecular modeling of NMR and ECD spectra and then confirmed through a straightforward enantioselective total synthesis of puna'auic acid featuring a key reductive opening of a propargylic epoxide.

Original languageEnglish
Pages (from-to)2311-2314
Number of pages4
JournalOrganic Letters
Volume20
Issue number8
DOIs
Publication statusPublished - 20 Apr 2018

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