SOURCES OF VARIABILITY IN THE ATRIAL PACING STRESS TEST (APST) IN PATIENTS WITH CORONARY ARTERY DISEASE.

G. T. Meester; S. H. Meij; P. W. Serruys; M. van den Brand; R. W. Brower

SOURCES OF VARIABILITY IN THE ATRIAL PACING STRESS TEST (APST) IN PATIENTS WITH CORONARY ARTERY DISEASE.

G. T. Meester
, S. H. Meij
, P. W. Serruys
, M. van den Brand
, R. W. Brower

Medicine

Research output: Contribution to a Journal (Peer & Non Peer) › Conference article › peer-review

Abstract

APST is used as a stress test to measure the dynamic response of the heart. It is considered to reflect the myocardial ″reserve capacity″ . Extensive intra- and interpatient variability may occur. An objective method to cope with this variability was assessed in the APST data of 44 normals and 71 patients with coronary artery disease (CAD) and compromised myocardial function. Reproducibility was tested with duplicate determinations in 10 CAD patients. Within a heart rate trajectory of 70 to 140 beats per minute, the relation between heart rate and LV pressure derived variables can be regarded as linear, both in normals and in patients with CAD. Results are reduced to measures of offset and slope. A further data reduction is carried out with linear multivariate discriminant analysis. The results are applicable as a scaled factor, indicating the extent of myocardial damage.

Original language	English
Pages (from-to)	241-244
Number of pages	4
Journal	Computers in Cardiology
Publication status	Published - 1980
Event	Unknown conference - Williamsburg, VA, USA Duration: 22 Oct 1980 → 24 Oct 1980

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Cite this

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title = "SOURCES OF VARIABILITY IN THE ATRIAL PACING STRESS TEST (APST) IN PATIENTS WITH CORONARY ARTERY DISEASE.",

abstract = "APST is used as a stress test to measure the dynamic response of the heart. It is considered to reflect the myocardial ″reserve capacity″ . Extensive intra- and interpatient variability may occur. An objective method to cope with this variability was assessed in the APST data of 44 normals and 71 patients with coronary artery disease (CAD) and compromised myocardial function. Reproducibility was tested with duplicate determinations in 10 CAD patients. Within a heart rate trajectory of 70 to 140 beats per minute, the relation between heart rate and LV pressure derived variables can be regarded as linear, both in normals and in patients with CAD. Results are reduced to measures of offset and slope. A further data reduction is carried out with linear multivariate discriminant analysis. The results are applicable as a scaled factor, indicating the extent of myocardial damage.",

author = "Meester, \{G. T.\} and Meij, \{S. H.\} and Serruys, \{P. W.\} and \{van den Brand\}, M. and Brower, \{R. W.\}",

year = "1980",

language = "English",

pages = "241--244",

journal = "Computers in Cardiology",

issn = "0276-6574",

publisher = "IEEE Computer Society",

note = "Unknown conference ; Conference date: 22-10-1980 Through 24-10-1980",

}

TY - JOUR

T1 - SOURCES OF VARIABILITY IN THE ATRIAL PACING STRESS TEST (APST) IN PATIENTS WITH CORONARY ARTERY DISEASE.

AU - Meester, G. T.

AU - Meij, S. H.

AU - Serruys, P. W.

AU - van den Brand, M.

AU - Brower, R. W.

PY - 1980

Y1 - 1980

N2 - APST is used as a stress test to measure the dynamic response of the heart. It is considered to reflect the myocardial ″reserve capacity″ . Extensive intra- and interpatient variability may occur. An objective method to cope with this variability was assessed in the APST data of 44 normals and 71 patients with coronary artery disease (CAD) and compromised myocardial function. Reproducibility was tested with duplicate determinations in 10 CAD patients. Within a heart rate trajectory of 70 to 140 beats per minute, the relation between heart rate and LV pressure derived variables can be regarded as linear, both in normals and in patients with CAD. Results are reduced to measures of offset and slope. A further data reduction is carried out with linear multivariate discriminant analysis. The results are applicable as a scaled factor, indicating the extent of myocardial damage.

AB - APST is used as a stress test to measure the dynamic response of the heart. It is considered to reflect the myocardial ″reserve capacity″ . Extensive intra- and interpatient variability may occur. An objective method to cope with this variability was assessed in the APST data of 44 normals and 71 patients with coronary artery disease (CAD) and compromised myocardial function. Reproducibility was tested with duplicate determinations in 10 CAD patients. Within a heart rate trajectory of 70 to 140 beats per minute, the relation between heart rate and LV pressure derived variables can be regarded as linear, both in normals and in patients with CAD. Results are reduced to measures of offset and slope. A further data reduction is carried out with linear multivariate discriminant analysis. The results are applicable as a scaled factor, indicating the extent of myocardial damage.

UR - https://www.scopus.com/pages/publications/0019286258

M3 - Conference article

AN - SCOPUS:0019286258

SN - 0276-6574

SP - 241

EP - 244

JO - Computers in Cardiology

JF - Computers in Cardiology

T2 - Unknown conference

Y2 - 22 October 1980 through 24 October 1980

ER -

SOURCES OF VARIABILITY IN THE ATRIAL PACING STRESS TEST (APST) IN PATIENTS WITH CORONARY ARTERY DISEASE.

Abstract

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