Sodwanone S, a triterpene from the marine sponge Axinella weltneri

Corinne Funel Le Bon; Fabrice Berrué; Olivier P. Thomas; Fernando Reyes; Philippe Amade

doi:10.1021/np050100o

Sodwanone S, a triterpene from the marine sponge Axinella weltneri

Corinne Funel Le Bon, Fabrice Berrué, Olivier P. Thomas, Fernando Reyes, Philippe Amade

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

26 Citations (Scopus)

Abstract

The bioassay-guided fractionation of the crude extract of the marine sponge Axinella weltneri led to the isolation and the identification of a new triterpene named sodwanone S (1), with an uncommon oxepane-cyclohexane system, along with the known sodwanones A and G. The structure was elucidated using spectroscopic data, and the biological activity was evaluated against 13 human tumor cell lines. A biogenetic pathway of this new compound is also proposed.

Original language	English
Pages (from-to)	1284-1287
Number of pages	4
Journal	Journal of Natural Products
Volume	68
Issue number	8
DOIs	https://doi.org/10.1021/np050100o
Publication status	Published - Aug 2005
Externally published	Yes

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abstract = "The bioassay-guided fractionation of the crude extract of the marine sponge Axinella weltneri led to the isolation and the identification of a new triterpene named sodwanone S (1), with an uncommon oxepane-cyclohexane system, along with the known sodwanones A and G. The structure was elucidated using spectroscopic data, and the biological activity was evaluated against 13 human tumor cell lines. A biogenetic pathway of this new compound is also proposed.",

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AU - Amade, Philippe

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AB - The bioassay-guided fractionation of the crude extract of the marine sponge Axinella weltneri led to the isolation and the identification of a new triterpene named sodwanone S (1), with an uncommon oxepane-cyclohexane system, along with the known sodwanones A and G. The structure was elucidated using spectroscopic data, and the biological activity was evaluated against 13 human tumor cell lines. A biogenetic pathway of this new compound is also proposed.

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Sodwanone S, a triterpene from the marine sponge Axinella weltneri

Abstract

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