Abstract
Background: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery.Methods: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.Results: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.Conclusion: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
| Original language | English (Ireland) |
|---|---|
| Media of output | Reviews |
| Publisher | Wiley |
| Volume | 105 |
| ISBN (Print) | 0007-1323 |
| ISBN (Electronic) | 0007-1323 |
| DOIs | |
| Publication status | Published - 1 Jan 2018 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- brca2 mutation carriers
- cells
- circulating micrornas
- early-stage
- expression
- lymph-node metastasis
- nuclear export
- receptor status
- tumor-suppressor
- up-regulation
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