Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.

Reilly E O'; Dhami SPS; Baev DV; C Ortutay; Anna Halpin-McCormick; R Morrell; C Santocanale; A Samali; John Quinn; O'Dwyer ME; E Szegezdi

doi:10.1038/s41598-018-33982-y

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.

Reilly E O'
, Dhami SPS
, Baev DV
, C Ortutay
, Anna Halpin-McCormick
, R Morrell
, C Santocanale
, A Samali
, John Quinn
, O'Dwyer ME
, E Szegezdi

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

Original language	Undefined/Unknown
Journal	Scientific Reports
DOIs	https://doi.org/10.1038/s41598-018-33982-y
Publication status	Published - Oct 2018

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10.1038/s41598-018-33982-y

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title = "Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.",

author = "O', \{Reilly E\} and Dhami SPS and Baev DV and C Ortutay and Anna Halpin-McCormick and R Morrell and C Santocanale and A Samali and John Quinn and O'Dwyer ME and E Szegezdi",

year = "2018",

month = oct,

doi = "10.1038/s41598-018-33982-y",

language = "Undefined/Unknown",

journal = "Scientific Reports",

issn = "2045-2322",

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T1 - Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.

AU - O', Reilly E

AU - SPS, Dhami

AU - DV, Baev

AU - Ortutay, C

AU - Halpin-McCormick, Anna

AU - Morrell, R

AU - Santocanale, C

AU - Samali, A

AU - Quinn, John

AU - ME, O'Dwyer

AU - Szegezdi, E

PY - 2018/10

Y1 - 2018/10

UR - http://europepmc.org/abstract/med/30361682

U2 - 10.1038/s41598-018-33982-y

DO - 10.1038/s41598-018-33982-y

M3 - Article

C2 - 30361682

SN - 2045-2322

JO - Scientific Reports

JF - Scientific Reports

ER -

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.

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