Repressed by a NuRD

Jeremy M. Crook; N. Ray Dunn; Alan Colman

doi:10.1038/ncb0306-212

Repressed by a NuRD

Jeremy M. Crook
, N. Ray Dunn
, Alan Colman

ES Cell International

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

16 Citations (Scopus)

Abstract

Embryonic stem (ES) cells deficient in Mbd3, a component of the nucleosome remodelling complex (NuRD), exhibit LIF-independent self-renewal and a restricted potential to differentiate. As such, it is likely that NuRD is required for ES cell pluripotency, and represents a potential link between maintaining the undifferentiated state and the capacity to differentiate.

Original language	English
Pages (from-to)	212-214
Number of pages	3
Journal	Nature Cell Biology
Volume	8
Issue number	3
DOIs	https://doi.org/10.1038/ncb0306-212
Publication status	Published - Mar 2006
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/ncb0306-212

Cite this

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title = "Repressed by a NuRD",

abstract = "Embryonic stem (ES) cells deficient in Mbd3, a component of the nucleosome remodelling complex (NuRD), exhibit LIF-independent self-renewal and a restricted potential to differentiate. As such, it is likely that NuRD is required for ES cell pluripotency, and represents a potential link between maintaining the undifferentiated state and the capacity to differentiate.",

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AU - Crook, Jeremy M.

AU - Ray Dunn, N.

AU - Colman, Alan

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AB - Embryonic stem (ES) cells deficient in Mbd3, a component of the nucleosome remodelling complex (NuRD), exhibit LIF-independent self-renewal and a restricted potential to differentiate. As such, it is likely that NuRD is required for ES cell pluripotency, and represents a potential link between maintaining the undifferentiated state and the capacity to differentiate.

UR - https://www.scopus.com/pages/publications/33646054905

U2 - 10.1038/ncb0306-212

DO - 10.1038/ncb0306-212

M3 - Article

C2 - 16508673

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JO - Nature Cell Biology

JF - Nature Cell Biology

IS - 3

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Repressed by a NuRD

Abstract

UN SDGs

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