Remote Preconditioning and Vascular Surgery: Challenges in Translation

Donagh A. Healy; Stewart R. Walsh

doi:10.1177/1074248417702892

Remote Preconditioning and Vascular Surgery: Challenges in Translation

Donagh A. Healy, Stewart R. Walsh

Research output: Contribution to a Journal (Peer & Non Peer) › Review article › peer-review

8 Citations (Scopus)

Abstract

Remote ischemic preconditioning (RIPC) is a theoretically attractive strategy for organ protection; and phase 2 studies in a variety of settings have yielded promising results. In this article, we review the existing clinical studies on RIPC in vascular surgery. We examine aspects of design that may potentially be optimized in future vascular surgery studies and we highlight some challenges that have emerged since the publication of the Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart) trial and the Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA) trial.

Original language	English
Pages (from-to)	316-320
Number of pages	5
Journal	Journal of Cardiovascular Pharmacology and Therapeutics
Volume	22
Issue number	4
DOIs	https://doi.org/10.1177/1074248417702892
Publication status	Published - 1 Jul 2017
Externally published	Yes

Keywords

cardioprotection
remote preconditioning
vascular surgery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/1074248417702892

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title = "Remote Preconditioning and Vascular Surgery: Challenges in Translation",

abstract = "Remote ischemic preconditioning (RIPC) is a theoretically attractive strategy for organ protection; and phase 2 studies in a variety of settings have yielded promising results. In this article, we review the existing clinical studies on RIPC in vascular surgery. We examine aspects of design that may potentially be optimized in future vascular surgery studies and we highlight some challenges that have emerged since the publication of the Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart) trial and the Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA) trial.",

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AU - Healy, Donagh A.

AU - Walsh, Stewart R.

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Y1 - 2017/7/1

N2 - Remote ischemic preconditioning (RIPC) is a theoretically attractive strategy for organ protection; and phase 2 studies in a variety of settings have yielded promising results. In this article, we review the existing clinical studies on RIPC in vascular surgery. We examine aspects of design that may potentially be optimized in future vascular surgery studies and we highlight some challenges that have emerged since the publication of the Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart) trial and the Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA) trial.

AB - Remote ischemic preconditioning (RIPC) is a theoretically attractive strategy for organ protection; and phase 2 studies in a variety of settings have yielded promising results. In this article, we review the existing clinical studies on RIPC in vascular surgery. We examine aspects of design that may potentially be optimized in future vascular surgery studies and we highlight some challenges that have emerged since the publication of the Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart) trial and the Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery (ERICCA) trial.

KW - cardioprotection

KW - remote preconditioning

KW - vascular surgery

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DO - 10.1177/1074248417702892

M3 - Review article

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EP - 320

JO - Journal of Cardiovascular Pharmacology and Therapeutics

JF - Journal of Cardiovascular Pharmacology and Therapeutics

IS - 4

ER -

Remote Preconditioning and Vascular Surgery: Challenges in Translation

Abstract

Keywords

UN SDGs

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