Receptors for Fc and complement in human breast carcinoma

D. T.L. Turner, C. E. Connolly, P. Isaacson, A. R. Turnbull

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

4 Citations (Scopus)

Abstract

Ninety seven human breast carcinomas have been examined for the presence of receptors for the crystallizable fragment (Fc) of immunoglobulin, and 82 of these have also been examined for receptors for complement by incubation of cryostat sections with appropriately coated sheep red cells. Ninety five of the 97 (98%) possessed Fc receptors on cells evenly distributed throughout the strom and 37/82 (45%) possessed complement receptors on infiltrating lymphocytes. Neither receptor was found on malignant epithelial cells. The Fc detector sheep red cells were bound less intensely to sections of primary tumor in which the axillary nodes were involved.

Original languageEnglish
Pages (from-to)87-92
Number of pages6
JournalClinical Oncology
Volume4
Issue number1
Publication statusPublished - 1978
Externally publishedYes

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