TY - JOUR
T1 - Re-appraisal of the nature of the pigment produced by Aeromonas salmonicida
AU - Donlon, John
AU - McGettigan, Seán
AU - O'Brien, Paul
AU - ÓCarra, Pádraig
PY - 1983
Y1 - 1983
N2 - Aeromonas salmonicida grown aerobically in the presence of tyrosine produces a dark-brown pigment, previously considered to be of a melanin type. However, this pigment is very water-soluble in contrast to melanin's solubility. In addition, no evidence for the presence of key early reactions and intermediates of the melanogensis pathway has been obtained. Radioisotopic labelling experiments, spectral data and chromatographic analyses support the conclusion that pigment biosynthesis, from tyrosine by Aeromonas salmonicida differs substantially from that of melanogenesis, and strongly suggest that the first intermediate is 2,4-dihydroxyphenylalanine and not 3,4-dihydroxyphenylalanine.
AB - Aeromonas salmonicida grown aerobically in the presence of tyrosine produces a dark-brown pigment, previously considered to be of a melanin type. However, this pigment is very water-soluble in contrast to melanin's solubility. In addition, no evidence for the presence of key early reactions and intermediates of the melanogensis pathway has been obtained. Radioisotopic labelling experiments, spectral data and chromatographic analyses support the conclusion that pigment biosynthesis, from tyrosine by Aeromonas salmonicida differs substantially from that of melanogenesis, and strongly suggest that the first intermediate is 2,4-dihydroxyphenylalanine and not 3,4-dihydroxyphenylalanine.
UR - http://www.scopus.com/inward/record.url?scp=0037623247&partnerID=8YFLogxK
U2 - 10.1111/j.1574-6968.1983.tb00558.x
DO - 10.1111/j.1574-6968.1983.tb00558.x
M3 - Article
AN - SCOPUS:0037623247
SN - 0378-1097
VL - 19
SP - 285
EP - 290
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
IS - 2-3
ER -