TY - JOUR
T1 - Promoting vascular regeneration as an alternative to conventional angioplasty-based intervention
AU - Noordeloos, Annemarie M.
AU - Soullié, Thomas
AU - Duckers, Henricus J.
AU - Serruys, P. W.J.C.
PY - 2006/11
Y1 - 2006/11
N2 - Technologies in interventional Cardiology have evolved from balloon to mechanical ablation, atherectomy, stenting, and brachytherapy to current drug eluting interventional strategies. New challenges are to develop techniques that not only prevent restenosis, but also promote vascular and endothelial healing after (balloon) injury. Endothelial healing approaches range from preventing endothelial injury to restoring endothelial function and reendothelialization by pharmacotherapy and cell therapy. These novel healing strategies warrant further exploration as they may represent an alternative to drug-eluting stent approaches.
AB - Technologies in interventional Cardiology have evolved from balloon to mechanical ablation, atherectomy, stenting, and brachytherapy to current drug eluting interventional strategies. New challenges are to develop techniques that not only prevent restenosis, but also promote vascular and endothelial healing after (balloon) injury. Endothelial healing approaches range from preventing endothelial injury to restoring endothelial function and reendothelialization by pharmacotherapy and cell therapy. These novel healing strategies warrant further exploration as they may represent an alternative to drug-eluting stent approaches.
KW - Drug eluting stents
KW - Endothelium
KW - Vascular healing
UR - http://www.scopus.com/inward/record.url?scp=33845616195&partnerID=8YFLogxK
U2 - 10.1080/10623320601066812
DO - 10.1080/10623320601066812
M3 - Article
C2 - 17169775
AN - SCOPUS:33845616195
SN - 1062-3329
VL - 13
SP - 431
EP - 439
JO - Endothelium: Journal of Endothelial Cell Research
JF - Endothelium: Journal of Endothelial Cell Research
IS - 6
ER -
