Prolonged acidosis is a feature of SGLT2i-induced euglycaemic diabetic ketoacidosis

Mohammed Faraz Rafey; Arslan Butt; Barry Coffey; Lisa Reddington; Aiden Devitt; David Lappin; Francis M. Finucane

doi:10.1530/EDM-19-0087

Prolonged acidosis is a feature of SGLT2i-induced euglycaemic diabetic ketoacidosis

Mohammed Faraz Rafey
, Arslan Butt
, Barry Coffey
, Lisa Reddington
, Aiden Devitt
, David Lappin
, Francis M. Finucane

Medicine

Galway University Hospital
University of Galway

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

16 Citations (Scopus)

Abstract

We describe two cases of SGLT2i-induced euglycaemic diabetic ketoacidosis, which took longer than we anticipated to treat despite initiation of our DKA protocol. Both patients had an unequivocal diagnosis of type 2 diabetes, had poor glycaemic control with a history of metformin intolerance and presented with relatively vague symptoms post-operatively. Neither patient had stopped their SGLT2i pre-operatively, but ought to have by current treatment guidelines.

Original language	English
Article number	19-0087
Journal	Endocrinology, Diabetes and Metabolism Case Reports
Volume	2019
Issue number	1
DOIs	https://doi.org/10.1530/EDM-19-0087
Publication status	Published - Jan 2019

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SDG 3 Good Health and Well-being

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10.1530/EDM-19-0087

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abstract = "We describe two cases of SGLT2i-induced euglycaemic diabetic ketoacidosis, which took longer than we anticipated to treat despite initiation of our DKA protocol. Both patients had an unequivocal diagnosis of type 2 diabetes, had poor glycaemic control with a history of metformin intolerance and presented with relatively vague symptoms post-operatively. Neither patient had stopped their SGLT2i pre-operatively, but ought to have by current treatment guidelines.",

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AU - Reddington, Lisa

AU - Devitt, Aiden

AU - Lappin, David

AU - Finucane, Francis M.

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AB - We describe two cases of SGLT2i-induced euglycaemic diabetic ketoacidosis, which took longer than we anticipated to treat despite initiation of our DKA protocol. Both patients had an unequivocal diagnosis of type 2 diabetes, had poor glycaemic control with a history of metformin intolerance and presented with relatively vague symptoms post-operatively. Neither patient had stopped their SGLT2i pre-operatively, but ought to have by current treatment guidelines.

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Prolonged acidosis is a feature of SGLT2i-induced euglycaemic diabetic ketoacidosis

Abstract

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