Progress towards the anatomy of the eukaryotic DNA replication fork

Heinz Peter Nasheuer; Helmut Pospiech; Juhani Syväoja

doi:10.1007/7050_016

Progress towards the anatomy of the eukaryotic DNA replication fork

Heinz Peter Nasheuer
, Helmut Pospiech
, Juhani Syväoja

Molecular Biosciences

University of Oulu
University of Eastern Finland

Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review

16 Citations (Scopus)

Abstract

During cell growth before each division, cells have to accurately duplicate their genome. The processes associated with DNA replication are tightly controlled; failure thereof can result in genome instability, which is a hallmark of cancer (Marte 2004). A large number of proteins are involved in this ambitious task to replicate the chromosomal DNA once and only once at a given time (Table 1).

Original language	English
Title of host publication	Genome Integrity
Editors	Dirk-Henner Lankenau
Pages	27-68
Number of pages	42
DOIs	https://doi.org/10.1007/7050_016
Publication status	Published - 2007

Publication series

Name	Genome Dynamics and Stability
Volume	1
ISSN (Print)	1861-3373
ISSN (Electronic)	1861-3381

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/7050_016

Cite this

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abstract = "During cell growth before each division, cells have to accurately duplicate their genome. The processes associated with DNA replication are tightly controlled; failure thereof can result in genome instability, which is a hallmark of cancer (Marte 2004). A large number of proteins are involved in this ambitious task to replicate the chromosomal DNA once and only once at a given time (Table 1).",

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AU - Nasheuer, Heinz Peter

AU - Pospiech, Helmut

AU - Syväoja, Juhani

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AB - During cell growth before each division, cells have to accurately duplicate their genome. The processes associated with DNA replication are tightly controlled; failure thereof can result in genome instability, which is a hallmark of cancer (Marte 2004). A large number of proteins are involved in this ambitious task to replicate the chromosomal DNA once and only once at a given time (Table 1).

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U2 - 10.1007/7050_016

DO - 10.1007/7050_016

M3 - Chapter

AN - SCOPUS:33750136263

SN - 3540375287

SN - 9783540375289

T3 - Genome Dynamics and Stability

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BT - Genome Integrity

A2 - Lankenau, Dirk-Henner

ER -

Progress towards the anatomy of the eukaryotic DNA replication fork

Abstract

Publication series

UN SDGs

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