Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ?-allylic amine

Frances Heaney; Sharon Bourke; Cathriona Burke; Desmond Cunningham; Patrick Mcardle

doi:10.13025/24347

Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ?-allylic amine

Frances Heaney
, Sharon Bourke
, Cathriona Burke
, Desmond Cunningham
, Patrick Mcardle

Cellular & Molecular Medicine

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

Abstract

Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular 'conjugate' addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

Original language	English (Ireland)
Journal	Journal Of The Chemical Society - Perkin Transactions 1
Issue number	15
DOIs	https://doi.org/10.13025/24347 https://doi.org/10.1039/a802750a
Publication status	Published - 1 Jan 1998

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10.13025/24347Licence: CC BY-NC-ND
10.1039/a802750a

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title = "Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ?-allylic amine",

abstract = "Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular 'conjugate' addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.",

author = "Frances Heaney and Sharon Bourke and Cathriona Burke and Desmond Cunningham and Patrick Mcardle",

year = "1998",

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T1 - Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ?-allylic amine

AU - Heaney, Frances

AU - Bourke, Sharon

AU - Burke, Cathriona

AU - Cunningham, Desmond

AU - Mcardle, Patrick

PY - 1998/1/1

Y1 - 1998/1/1

N2 - Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular 'conjugate' addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

AB - Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular 'conjugate' addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

UR - http://hdl.handle.net/10379/9278

U2 - 10.13025/24347

DO - 10.13025/24347

M3 - Article

JO - Journal Of The Chemical Society - Perkin Transactions 1

JF - Journal Of The Chemical Society - Perkin Transactions 1

IS - 15

ER -

Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ?-allylic amine

Abstract

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