Practical Bioinformatics Analysis of MiRNA Data Using Online Tools

Emer Bourke

doi:10.1007/978-1-4939-6524-3_18

Practical Bioinformatics Analysis of MiRNA Data Using Online Tools

Emer Bourke

Pathology

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Abstract

The purpose of this chapter is to provide a starting point for the analysis of miRNA array data, using freely available online suites of tools. This chapter does not describe how to perform analysis of primary array data, rather how to use the top differentially regulated miRNA (returned from comparing one miRNA group to another) as the starting point for further practical analysis.Here we describe the methods and tools required to identify targets worthy of additional investigation, using the identified miRNA as a starting point. Importantly, this additional information (pathways targeted, gene expression, mRNA targets, miRNA families) can be used to positively inform any project.

Original language	English (Ireland)
Number of pages	13
Journal	Methods in Molecular Biology
Volume	1509
DOIs	https://doi.org/10.1007/978-1-4939-6524-3_18
Publication status	Published - 1 Jan 2017

Authors (Note for portal: view the doc link for the full list of authors)

Authors
Brown, JAL;Bourke, E

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10.1007/978-1-4939-6524-3_18

Cite this

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abstract = "The purpose of this chapter is to provide a starting point for the analysis of miRNA array data, using freely available online suites of tools. This chapter does not describe how to perform analysis of primary array data, rather how to use the top differentially regulated miRNA (returned from comparing one miRNA group to another) as the starting point for further practical analysis.Here we describe the methods and tools required to identify targets worthy of additional investigation, using the identified miRNA as a starting point. Importantly, this additional information (pathways targeted, gene expression, mRNA targets, miRNA families) can be used to positively inform any project.",

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AB - The purpose of this chapter is to provide a starting point for the analysis of miRNA array data, using freely available online suites of tools. This chapter does not describe how to perform analysis of primary array data, rather how to use the top differentially regulated miRNA (returned from comparing one miRNA group to another) as the starting point for further practical analysis.Here we describe the methods and tools required to identify targets worthy of additional investigation, using the identified miRNA as a starting point. Importantly, this additional information (pathways targeted, gene expression, mRNA targets, miRNA families) can be used to positively inform any project.

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Practical Bioinformatics Analysis of MiRNA Data Using Online Tools

Abstract

Authors (Note for portal: view the doc link for the full list of authors)

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