Polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane

Jose Varghese; Pachiannan Sakthipriya; Gunalan Rachel; Nallamuthu Ananthi

Polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane

Jose Varghese
, Pachiannan Sakthipriya
, Gunalan Rachel
, Nallamuthu Ananthi

Department of Nanoscience and Nanotechnology
Karunya University

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

6 Citations (Scopus)

Abstract

In the present study, a pH responsive polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane is reported. PLA has been coated on the functionalized SBA-15 by formation of amide linkage between amine functionalized SBA-15 and PLA. The amide linkage is confirmed by FTIR spectroscopic data. The materials are well characterized by FTIR, SEM, EDAX and XRD data. Using the PLA coated functionalized SBA-15 the controlled release of the drug ibuprofen has been studied. The successful delivery of ibuprofen has been achieved on the basis of its pH response.

Original language	English
Pages (from-to)	621-625
Number of pages	5
Journal	Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry
Volume	56A
Issue number	6
Publication status	Published - Jun 2017
Externally published	Yes

Keywords

Drug delivery
Functionalized SBA-15
Mesoporous materials
Mesoporous silica
SBA-15
Silica

Cite this

@article{9e65fa86f2384d7baa8486a1be22bddb,

title = "Polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane",

abstract = "In the present study, a pH responsive polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane is reported. PLA has been coated on the functionalized SBA-15 by formation of amide linkage between amine functionalized SBA-15 and PLA. The amide linkage is confirmed by FTIR spectroscopic data. The materials are well characterized by FTIR, SEM, EDAX and XRD data. Using the PLA coated functionalized SBA-15 the controlled release of the drug ibuprofen has been studied. The successful delivery of ibuprofen has been achieved on the basis of its pH response.",

keywords = "Drug delivery, Functionalized SBA-15, Mesoporous materials, Mesoporous silica, SBA-15, Silica",

author = "Jose Varghese and Pachiannan Sakthipriya and Gunalan Rachel and Nallamuthu Ananthi",

year = "2017",

month = jun,

language = "English",

volume = "56A",

pages = "621--625",

journal = "Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry",

issn = "0376-4710",

publisher = "Scientific Publishers of India",

number = "6",

}

Polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane. / Varghese, Jose; Sakthipriya, Pachiannan; Rachel, Gunalan et al.
In: Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, Vol. 56A, No. 6, 06.2017, p. 621-625.

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

TY - JOUR

T1 - Polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane

AU - Varghese, Jose

AU - Sakthipriya, Pachiannan

AU - Rachel, Gunalan

AU - Ananthi, Nallamuthu

PY - 2017/6

Y1 - 2017/6

N2 - In the present study, a pH responsive polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane is reported. PLA has been coated on the functionalized SBA-15 by formation of amide linkage between amine functionalized SBA-15 and PLA. The amide linkage is confirmed by FTIR spectroscopic data. The materials are well characterized by FTIR, SEM, EDAX and XRD data. Using the PLA coated functionalized SBA-15 the controlled release of the drug ibuprofen has been studied. The successful delivery of ibuprofen has been achieved on the basis of its pH response.

AB - In the present study, a pH responsive polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane is reported. PLA has been coated on the functionalized SBA-15 by formation of amide linkage between amine functionalized SBA-15 and PLA. The amide linkage is confirmed by FTIR spectroscopic data. The materials are well characterized by FTIR, SEM, EDAX and XRD data. Using the PLA coated functionalized SBA-15 the controlled release of the drug ibuprofen has been studied. The successful delivery of ibuprofen has been achieved on the basis of its pH response.

KW - Drug delivery

KW - Functionalized SBA-15

KW - Mesoporous materials

KW - Mesoporous silica

KW - SBA-15

KW - Silica

UR - https://www.scopus.com/pages/publications/85026248208

M3 - Article

AN - SCOPUS:85026248208

SN - 0376-4710

VL - 56A

SP - 621

EP - 625

JO - Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry

JF - Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry

IS - 6

ER -

Polylactic acid coated SBA-15 functionalized with 3-aminopropyl triethoxysilane

Abstract

Keywords

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