Pluripotent Stem Cells and Disease Modeling

Alan Colman; Oliver Dreesen

doi:10.1016/j.stem.2009.08.010

Pluripotent Stem Cells and Disease Modeling

Alan Colman
, Oliver Dreesen

Research output: Contribution to a Journal (Peer & Non Peer) › Comment/debate

87 Citations (Scopus)

Abstract

Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease.

Original language	English
Pages (from-to)	244-247
Number of pages	4
Journal	Cell Stem Cell
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.stem.2009.08.010
Publication status	Published - 4 Sep 2009
Externally published	Yes

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10.1016/j.stem.2009.08.010

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title = "Pluripotent Stem Cells and Disease Modeling",

abstract = "Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease.",

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AU - Dreesen, Oliver

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AB - Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease.

UR - https://www.scopus.com/pages/publications/69249208658

U2 - 10.1016/j.stem.2009.08.010

DO - 10.1016/j.stem.2009.08.010

M3 - Comment/debate

C2 - 19733533

AN - SCOPUS:69249208658

SN - 1934-5909

VL - 5

SP - 244

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JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 3

ER -

Pluripotent Stem Cells and Disease Modeling

Abstract

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