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Peptide growth factors and preimplantation development

  • Marian Kane
    • University of Galway

    Research output: Contribution to a Journal (Peer & Non Peer)Review articlepeer-review

    216 Citations (Scopus)

    Abstract

    This paper examines some of the problems and questions that must be considered in relation to research on the role of growth factors in preimplantation embryos. It reviews and summarizes the large body of work on gene expression of growth factor receptors and ligands in preimplantation embryos and in oviduct and uterine tissue. It also reviews the literature on the effects of gene knockout in preimplantation embryos and concludes with a review of work on the effects of growth factors on cultured embryos.

    Original languageEnglish
    Pages (from-to)137-157
    Number of pages21
    JournalHuman Reproduction Update
    Volume3
    Issue number2
    DOIs
    Publication statusPublished - Mar 1997

    Keywords

    • Development
    • Embryo
    • Embryo culture
    • Gene expression
    • Growth factor

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