Abstract
This paper examines some of the problems and questions that must be considered in relation to research on the role of growth factors in preimplantation embryos. It reviews and summarizes the large body of work on gene expression of growth factor receptors and ligands in preimplantation embryos and in oviduct and uterine tissue. It also reviews the literature on the effects of gene knockout in preimplantation embryos and concludes with a review of work on the effects of growth factors on cultured embryos.
| Original language | English |
|---|---|
| Pages (from-to) | 137-157 |
| Number of pages | 21 |
| Journal | Human Reproduction Update |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 1997 |
Keywords
- Development
- Embryo
- Embryo culture
- Gene expression
- Growth factor
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