Abstract
The role of parathyroid hormone related protein (PTHRP) as a humoral mediator of hypercalcaemia was investigated in a patient with lymphocyte depleted Hodgkin's disease during an episode of hypercalcaemia, using an immunohistochemical staining technique for PTHRP on the tumour tissue and an immunoradiometric (IRMA) assay for PTHRP1-86 on the patient's plasma. The plasma PTHRP was less than 0.23 pmol/l in the range found in normocalcaemic controls, and the immunohistochemical staining was not positive for protein. PTHRP did not have a role in the pathogenesis of hypercalcaemia in this patient.
| Original language | English |
|---|---|
| Pages (from-to) | 541-542 |
| Number of pages | 2 |
| Journal | Journal of Clinical Pathology |
| Volume | 45 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1992 |
| Externally published | Yes |
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