Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks

Anthony W. O'Regan; Gerard J. Nau; Geoffrey L. Chupp; Jeffrey S. Berman

doi:10.1016/S0167-5699(00)01715-1

Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks

Anthony W. O'Regan
, Gerard J. Nau
, Geoffrey L. Chupp
, Jeffrey S. Berman

Boston University School of Medicine
Whitehead Institute
Massachusetts General Hospital
Yale University School of Medicine

Research output: Contribution to a Journal (Peer & Non Peer) › Short survey › peer-review

163 Citations (Scopus)

Abstract

Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.

Original language	English
Pages (from-to)	475-478
Number of pages	4
Journal	Immunology Today
Volume	21
Issue number	10
DOIs	https://doi.org/10.1016/S0167-5699(00)01715-1
Publication status	Published - 2000
Externally published	Yes

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10.1016/S0167-5699(00)01715-1

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title = "Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks",

abstract = "Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.",

author = "O'Regan, \{Anthony W.\} and Nau, \{Gerard J.\} and Chupp, \{Geoffrey L.\} and Berman, \{Jeffrey S.\}",

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T1 - Osteopontin (Eta-I) in cell-mediated immunity

T2 - Teaching an old dog new tricks

AU - O'Regan, Anthony W.

AU - Nau, Gerard J.

AU - Chupp, Geoffrey L.

AU - Berman, Jeffrey S.

PY - 2000

Y1 - 2000

N2 - Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.

AB - Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.

UR - https://www.scopus.com/pages/publications/0033623454

U2 - 10.1016/S0167-5699(00)01715-1

DO - 10.1016/S0167-5699(00)01715-1

M3 - Short survey

C2 - 11071524

AN - SCOPUS:0033623454

SN - 0167-5699

VL - 21

SP - 475

EP - 478

JO - Immunology Today

JF - Immunology Today

IS - 10

ER -

Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks

Abstract

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