OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III

SERGEY ALEXANDROV

doi:10.1117/12.2210964

OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III

SERGEY ALEXANDROV

Physics

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

Abstract

Optical coherence elastography (OCE) asesses the mechanical properties of samples by applying a mechanical stimulation and detecting the resulting sample displacement using optical coherence tomography (OCT). OCE methods which utilise the phase of the OCT signal offer the potential to detect displacements on the sub-nanometre scale. However, the displacement sensitivity achieveable is directly related to the signal-to-noise ratio and phase stability of the underlying OCT system. Furthermore, the estimation of Doppler angle is imperative in accurately measuring the sample displacement. This work evaluates the contributions of each of these parameters for quantitative assessment of mechanical properties using phase-sensitive spectral domain OCT.

Original language	English (Ireland)
Title of host publication	Depth-dependent displacement sensitivity analysis and the influence of Doppler angle for quantitative assessment of mechanical properties using phase-sensitive spectral domain optical coherence tomography
Volume	9710
DOIs	https://doi.org/10.1117/12.2210964
Publication status	Published - 1 Oct 2016

Authors (Note for portal: view the doc link for the full list of authors)

Authors
Lynch, G,Subhash, H,Alexandrov, S,Leahy, M,Larin, KV,Sampson, DD

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10.1117/12.2210964

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title = "OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III",

abstract = "Optical coherence elastography (OCE) asesses the mechanical properties of samples by applying a mechanical stimulation and detecting the resulting sample displacement using optical coherence tomography (OCT). OCE methods which utilise the phase of the OCT signal offer the potential to detect displacements on the sub-nanometre scale. However, the displacement sensitivity achieveable is directly related to the signal-to-noise ratio and phase stability of the underlying OCT system. Furthermore, the estimation of Doppler angle is imperative in accurately measuring the sample displacement. This work evaluates the contributions of each of these parameters for quantitative assessment of mechanical properties using phase-sensitive spectral domain OCT.",

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OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III. / ALEXANDROV, SERGEY.
Depth-dependent displacement sensitivity analysis and the influence of Doppler angle for quantitative assessment of mechanical properties using phase-sensitive spectral domain optical coherence tomography. Vol. 9710 2016.

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

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N2 - Optical coherence elastography (OCE) asesses the mechanical properties of samples by applying a mechanical stimulation and detecting the resulting sample displacement using optical coherence tomography (OCT). OCE methods which utilise the phase of the OCT signal offer the potential to detect displacements on the sub-nanometre scale. However, the displacement sensitivity achieveable is directly related to the signal-to-noise ratio and phase stability of the underlying OCT system. Furthermore, the estimation of Doppler angle is imperative in accurately measuring the sample displacement. This work evaluates the contributions of each of these parameters for quantitative assessment of mechanical properties using phase-sensitive spectral domain OCT.

AB - Optical coherence elastography (OCE) asesses the mechanical properties of samples by applying a mechanical stimulation and detecting the resulting sample displacement using optical coherence tomography (OCT). OCE methods which utilise the phase of the OCT signal offer the potential to detect displacements on the sub-nanometre scale. However, the displacement sensitivity achieveable is directly related to the signal-to-noise ratio and phase stability of the underlying OCT system. Furthermore, the estimation of Doppler angle is imperative in accurately measuring the sample displacement. This work evaluates the contributions of each of these parameters for quantitative assessment of mechanical properties using phase-sensitive spectral domain OCT.

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DO - 10.1117/12.2210964

M3 - Conference Publication

VL - 9710

BT - Depth-dependent displacement sensitivity analysis and the influence of Doppler angle for quantitative assessment of mechanical properties using phase-sensitive spectral domain optical coherence tomography

ER -

OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III

Abstract

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