OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XXIV

SERGEY ALEXANDROV; Martin Leahy

doi:10.1117/12.2543398

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XXIV

SERGEY ALEXANDROV
, Martin Leahy

Physics

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

Abstract

In biomedical optics, Optical Coherence Tomography (OCT) is an emerging optical imaging modality during the last three decades. OCT can perform high resolution, cross-section imaging of the internal microstructure in biological tissues by measuring echoes of backscattered light. We have developed a broadband, high-resolution spectral domain OCT system whose central wavelength is 1300 nm with bandwidth similar to 400 nm. Theoretical axial resolution of the system is similar to 3.71 mu m and experimentally we get similar to 5 mu m in air. Furthermore, we will apply this system for nano-sensitive detection and visualization in varieties of biological tissues.

Original language	English (Ireland)
Title of host publication	Development of HR-SD-OCT system using supercontinuum light source and its application in detecting nanoscale changes
Volume	11228
DOIs	https://doi.org/10.1117/12.2543398
Publication status	Published - 1 Feb 2020

Authors (Note for portal: view the doc link for the full list of authors)

Authors
Dey, R,Zhou, Y,Das, N,Alexandrov, S,Nolan, A,Neuhaus, K,Leahy, M,Izatt, JA,Fujimoto, JG

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10.1117/12.2543398

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title = "OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XXIV",

abstract = "In biomedical optics, Optical Coherence Tomography (OCT) is an emerging optical imaging modality during the last three decades. OCT can perform high resolution, cross-section imaging of the internal microstructure in biological tissues by measuring echoes of backscattered light. We have developed a broadband, high-resolution spectral domain OCT system whose central wavelength is 1300 nm with bandwidth similar to 400 nm. Theoretical axial resolution of the system is similar to 3.71 mu m and experimentally we get similar to 5 mu m in air. Furthermore, we will apply this system for nano-sensitive detection and visualization in varieties of biological tissues.",

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OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XXIV. / ALEXANDROV, SERGEY; Leahy, Martin.
Development of HR-SD-OCT system using supercontinuum light source and its application in detecting nanoscale changes. Vol. 11228 2020.

Research output: Chapter in Book or Conference Publication/Proceeding › Conference Publication › peer-review

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N2 - In biomedical optics, Optical Coherence Tomography (OCT) is an emerging optical imaging modality during the last three decades. OCT can perform high resolution, cross-section imaging of the internal microstructure in biological tissues by measuring echoes of backscattered light. We have developed a broadband, high-resolution spectral domain OCT system whose central wavelength is 1300 nm with bandwidth similar to 400 nm. Theoretical axial resolution of the system is similar to 3.71 mu m and experimentally we get similar to 5 mu m in air. Furthermore, we will apply this system for nano-sensitive detection and visualization in varieties of biological tissues.

AB - In biomedical optics, Optical Coherence Tomography (OCT) is an emerging optical imaging modality during the last three decades. OCT can perform high resolution, cross-section imaging of the internal microstructure in biological tissues by measuring echoes of backscattered light. We have developed a broadband, high-resolution spectral domain OCT system whose central wavelength is 1300 nm with bandwidth similar to 400 nm. Theoretical axial resolution of the system is similar to 3.71 mu m and experimentally we get similar to 5 mu m in air. Furthermore, we will apply this system for nano-sensitive detection and visualization in varieties of biological tissues.

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DO - 10.1117/12.2543398

M3 - Conference Publication

VL - 11228

BT - Development of HR-SD-OCT system using supercontinuum light source and its application in detecting nanoscale changes

ER -

OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XXIV

Abstract

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