@inproceedings{3906ac663f4549c2adb32a98e86bc332,
title = "Novel contrast mechanism for label free super-resolution imaging",
abstract = "We present a novel super-resolution spectral encoding of spatial frequency (srSESF) approach to break the diffraction limit and dramatically improve resolution in lateral direction. The idea is to utilize additional information about the internal structure of the object to resolve features in the lateral direction. The novel contrast mechanism is realized by reconstruction and comparison of the axial spatial frequency (period) profiles at each image point to form super-resolution image. As a result, small features, unresolved by conventional microscopy, can be visualized. Numerical simulation and experiments confirm the super-resolution abilities of the srSESF approach without applying any labels.",
keywords = "Optical microscopy, label-free imaging, super-resolution.",
author = "Alexandrov, \{Sergey A.\} and James McGrath and Hrebesh Subhash and Francesca Boccafoschi and Cinzia Giannini and Martin Leahy",
note = "Publisher Copyright: {\textcopyright} 2016 SPIE.; Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXIII ; Conference date: 15-02-2016 Through 17-02-2016",
year = "2016",
doi = "10.1117/12.2207458",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Cogswell, \{Carol J.\} and Tony Wilson and Brown, \{Thomas G.\}",
booktitle = "Three-Dimensional and Multidimensional Microscopy",
}