TY - GEN
T1 - Multi-stage, solvent-controlled routing for automated on-disc extraction of total RNA from breast cancer cell line homogenate
AU - Gaughran, J.
AU - Dimov, N.
AU - Clancy, E.
AU - Barry, T.
AU - Smith, T. J.
AU - Ducree, J.
PY - 2013
Y1 - 2013
N2 - We report for the first time rotationally controlled extraction of total RNA from cell homogenate through novel, solvent-dependent routing on a centrifugal micro-fluidic platform. This system allows for sample preparation and integrated analysis to be incorporated on a single microfluidic device. Also reported here for the first time is a solvent-triggered valving mechanism and the performance of on-disc extraction of purified total RNA.
AB - We report for the first time rotationally controlled extraction of total RNA from cell homogenate through novel, solvent-dependent routing on a centrifugal micro-fluidic platform. This system allows for sample preparation and integrated analysis to be incorporated on a single microfluidic device. Also reported here for the first time is a solvent-triggered valving mechanism and the performance of on-disc extraction of purified total RNA.
KW - centrifugal microfluidics
KW - solvent dependent routing
KW - solvent triggered valving
KW - Total RNA extraction
UR - https://www.scopus.com/pages/publications/84891704194
U2 - 10.1109/Transducers.2013.6626763
DO - 10.1109/Transducers.2013.6626763
M3 - Conference Publication
AN - SCOPUS:84891704194
SN - 9781467359818
T3 - 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
SP - 305
EP - 308
BT - 2013 Transducers and Eurosensors XXVII
T2 - 2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Y2 - 16 June 2013 through 20 June 2013
ER -
