Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.

Karim Sallam; Dilip Thomas; Sadhana Gaddam; Nicole Lopez; Aimee Beck; Leila Beach; Albert J Rogers; Hao Zhang; Ian Y Chen; Mohamed Ameen; William Hiesinger; Jeffrey J Teuteberg; June-Wha W Rhee; Kevin C Wang; Nazish Sayed; Joseph C Wu

doi:10.1161/CIRCULATIONAHA.121.054317

Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.

Karim Sallam
, Dilip Thomas
, Sadhana Gaddam
, Nicole Lopez
, Aimee Beck
, Leila Beach
, Albert J Rogers
, Hao Zhang
, Ian Y Chen
, Mohamed Ameen
, William Hiesinger
, Jeffrey J Teuteberg
, June-Wha W Rhee
, Kevin C Wang
, Nazish Sayed
, Joseph C Wu

Pharmacology

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

21 Citations (Scopus)

Original language	Undefined/Unknown
Journal	Circulation
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.121.054317
Publication status	Published - 26 Apr 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1161/CIRCULATIONAHA.121.054317

Cite this

Sallam, K., Thomas, D., Gaddam, S., Lopez, N., Beck, A., Beach, L., Rogers, A. J., Zhang, H., Chen, I. Y., Ameen, M., Hiesinger, W., Teuteberg, J. J., Rhee, J.-W. W., Wang, K. C., Sayed, N., & Wu, J. C. (2022). Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing. Circulation. https://doi.org/10.1161/CIRCULATIONAHA.121.054317

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title = "Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.",

author = "Karim Sallam and Dilip Thomas and Sadhana Gaddam and Nicole Lopez and Aimee Beck and Leila Beach and Rogers, \{Albert J\} and Hao Zhang and Chen, \{Ian Y\} and Mohamed Ameen and William Hiesinger and Teuteberg, \{Jeffrey J\} and Rhee, \{June-Wha W\} and Wang, \{Kevin C\} and Nazish Sayed and Wu, \{Joseph C\}",

year = "2022",

month = apr,

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doi = "10.1161/CIRCULATIONAHA.121.054317",

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Sallam, K, Thomas, D, Gaddam, S, Lopez, N, Beck, A, Beach, L, Rogers, AJ, Zhang, H, Chen, IY, Ameen, M, Hiesinger, W, Teuteberg, JJ, Rhee, J-WW, Wang, KC, Sayed, N & Wu, JC 2022, 'Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.', Circulation. https://doi.org/10.1161/CIRCULATIONAHA.121.054317

TY - JOUR

T1 - Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing.

AU - Sallam, Karim

AU - Thomas, Dilip

AU - Gaddam, Sadhana

AU - Lopez, Nicole

AU - Beck, Aimee

AU - Beach, Leila

AU - Rogers, Albert J

AU - Zhang, Hao

AU - Chen, Ian Y

AU - Ameen, Mohamed

AU - Hiesinger, William

AU - Teuteberg, Jeffrey J

AU - Rhee, June-Wha W

AU - Wang, Kevin C

AU - Sayed, Nazish

AU - Wu, Joseph C

PY - 2022/4/26

Y1 - 2022/4/26

U2 - 10.1161/CIRCULATIONAHA.121.054317

DO - 10.1161/CIRCULATIONAHA.121.054317

M3 - Article

C2 - 35467958

SN - 1524-4539

JO - Circulation

JF - Circulation

ER -