Abstract
Mitochondria are much
studied organelles, investigated for decades
for their vital role
as powerhouses of the cell and for the evolutionary
history concealed in
the mitochondrial genome. To this day, research
on mitochondria is
still yielding fascinating new information. Over the
past two decades a
large body of evidence has been accumulated
showing these
structures, which are at the heart of metabolic
processes sustaining
life, at same time containing the seeds of
cellular
self-destruction. This chapter describes the death-inducing
proteins that are
released from mitochondria, the mechanisms of
release, as well as
how release is regulated. Finally, phytochemicals
that affect the
release of lethal mitochondrial proteins are discussed.
| Original language | English (Ireland) |
|---|---|
| Title of host publication | Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy |
| Publisher | Springer |
| Publication status | Published - 1 Jan 2013 |
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Richard Jaeger and Howard O. Fearnhead