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Mesenchymal stem cells in regenerative medicine

  • University of Galway

Research output: Chapter in Book or Conference Publication/Proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

Cellular therapy involves the isolation, expansion and transplantation of human cells for the replacement or regeneration of injured tissues. It is one of the most significant repair strategies in Regenerative Medicine today. Mesenchymal stem cells represent a versatile, multimodal cellular therapy for the treatment of a broad spectrum of diseases. They stimulate a host repair response by paracrine mechanisms involving immunomodulatory, cytoprotective and pro-angiogenic mechanisms. It also appears that they may be tolerated as a fully allogeneic therapy.

Original languageEnglish
Title of host publicationRegenerative Medicine and Cell Therapy
EditorsJean-Francois Stoltz, Jean-Francois Stoltz
Pages51-61
Number of pages11
DOIs
Publication statusPublished - 2012

Publication series

NameBiomedical and Health Research
ISSN (Print)0929-6743
ISSN (Electronic)1879-8098

Keywords

  • cardiac repair
  • Cellular therapy
  • mesenchymal stem cells
  • osteoarthritis
  • paracrine mechanisms

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