Abstract
MMC, the addition of inert polydispersed macromolecules in the culture media, effectively emulates the dense in vivo extracellular space, resulting in amplified deposition of ECM in vitro and subsequent production of cohesive, ECM-rich living substitutes.
| Original language | English (Ireland) |
|---|---|
| Pages (from-to) | 3024-3034 |
| Number of pages | 11 |
| Journal | Advanced Materials |
| Volume | 26 |
| Issue number | 19 |
| DOIs | |
| Publication status | Published - 1 May 2014 |
Keywords
- cell-sheet tissue engineering
- excluding volume effect
- extracellular matrix deposition
- macromolecular crowding
- macromolecular polydispersity
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Satyam A, Kumar P, Fan X, Gorelov A, Rochev Y, Joshi L, Peinado H, Lyden D, Thomas B, Rodriguez B, Raghunath M, Pandit A, Zeugolis D