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Lipase catalysed resolution of ferrocene cyanohydrin: Access to novel ferrocenyl aminoalcohols and diamines

  • Patrick Mcardle

Research output: Contribution to a Journal (Peer & Non Peer)Articlepeer-review

Abstract

(R)-(+)-Ferrocene cyanohydrin acetate, obtained by enzymatic acylation of ferrocene cyanohydrin, may be transformed by reduction and alkylation into novel ferrocenyl P-aminoalcohols. Substitution of acetate by methanolic HNMe2 proceeds with racemisation, but significant diastereoselection is observed on Strecker reaction using (-)-PhCH(Me)NHMe. (C) 1997 Elsevier Science Ltd.
Original languageEnglish (Ireland)
Number of pages4
JournalTETRAHEDRON-ASYMMETRY
Volume8
Publication statusPublished - 1 Apr 1997

Authors (Note for portal: view the doc link for the full list of authors)

  • Authors
  • Howell, JAS,Humphries, K,McArdle, P,Cunningham, D,Nicolosi, G,Patti, A,Walsh, MA

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