Iso-, nor-, and dinor-spiculoic acids A, polyketides from the marine sponge Plakortis zyggompha

Fabrice Berrué; Olivier P. Thomas; Rogelio Fernández; Philippe Amade

doi:10.1021/np049602c

Iso-, nor-, and dinor-spiculoic acids A, polyketides from the marine sponge Plakortis zyggompha

Fabrice Berrué, Olivier P. Thomas, Rogelio Fernández, Philippe Amade

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

17 Citations (Scopus)

Abstract

The new iso-, nor-, and dinor-spiculoic acids A (1, 2, and 3, respectively) with a rare spiculane skeleton were isolated from the marine sponge Plakortis zyggompha, collected in the waters south of Martinique. The structural determination of the compounds was based on 1D and 2D NMR studies and mass spectral determinations. Compounds 1 and 2 showed weak cytotoxicity against the two tumor cell lines A549 and HT29.

Original language	English
Pages (from-to)	547-549
Number of pages	3
Journal	Journal of Natural Products
Volume	68
Issue number	4
DOIs	https://doi.org/10.1021/np049602c
Publication status	Published - Apr 2005
Externally published	Yes

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AU - Amade, Philippe

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Iso-, nor-, and dinor-spiculoic acids A, polyketides from the marine sponge Plakortis zyggompha

Abstract

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