Abstract
Current guidelines do not recommend locoregional surgery for Stage IV breast cancer at presentation despite some studies suggesting a survival benefit. We aimed to assess outcomes in patients with Stage IV breast cancer who underwent surgery.In a cohort study of all Stage IV breast cancers diagnosed at our tertiary-referral specialist centre between 2006 and 2012, we assessed patient survival in the context of demographics, histopathology, metastatic burden, and type of surgery performed.One hundred and nine patients were included; 52 underwent surgery. Patients in the surgery group had longer 5-year-survival (p=0.003). Survival was also significantly longer in those with just one site of metastatic disease (p<0.001). Patients with axillary cytology positive for regional metastases were less likely to proceed to surgery.Locoregional surgery does confer a survival advantage in Stage IV breast cancer. Assessment of preoperative axillary cytology may preclude some patients from proceeding to potentially beneficial locoregional surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 32-37 |
| Number of pages | 6 |
| Journal | Breast |
| Volume | 24 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Feb 2015 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Axillary fine needle aspiration cytology
- Breast surgery
- Metastatic breast cancer
- Stage IV breast cancer
Authors (Note for portal: view the doc link for the full list of authors)
- Authors
- Quinn, EM,Kealy, R,O'Meara, S,Whelan, M,Ennis, R,Malone, C,McLaughlin, R,Kerin, MJ,Sweeney, KJ
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