Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

E. Kotsiliti; V. Leone; S. Schuehle; O. Govaere; H. Li; M.J. Wolf; H. Horvatic; S. Bierwirth; J. Hundertmark; D. Inverso; L. Zizmare; A. Sarusi-Portuguez; R. Gupta; T. O'Connor; A.D. Giannou; A.M. Shiri; Y. Schlesinger; M.G. Beccaria; C. Rennert; D. Pfister; R. Öllinger; I. Gadjalova; P. Ramadori; M. Rahbari; N. Rahbari; M.E. Healy; M. Fernández-Vaquero; N. Yahoo; J. Janzen; I. Singh; C. Fan; M. Rau; M. Feuchtenberger; E. Schwaneck; S. Cockell; J. Wilson-Kanamori; P. Ramachandran; C. Kho; T.J. Kendall; A.-L. Leblond; S.J. Keppler; P. Bielecki; K. Steiger; M. Hofmann; K. Rippe; H. Zitzelsberger; A. Weber; N. Malek; T. Luedde; M. Vucur; H.G. Augustin; R. Flavell; O. Parnas; R. Rad; O. Pabst; N.C. Henderson; S. Huber; A. Macpherson; P. Knolle; M. Claassen; A. Geier; C. Trautwein; K. Unger; E. Elinav; A. Waisman; Z. Abdullah; D. Haller; F. Tacke; Q.M. Anstee; M. Heikenwalder

doi:10.1016/j.jhep.2023.04.037

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

E. Kotsiliti
, V. Leone
, S. Schuehle
, O. Govaere
, H. Li
, M.J. Wolf
, H. Horvatic
, S. Bierwirth
, J. Hundertmark
, D. Inverso
, L. Zizmare
, A. Sarusi-Portuguez
, R. Gupta
, T. O'Connor
, A.D. Giannou
, A.M. Shiri
, Y. Schlesinger
, M.G. Beccaria
, C. Rennert
, D. Pfister

R. Öllinger, I. Gadjalova, P. Ramadori, M. Rahbari, N. Rahbari, M.E. Healy, M. Fernández-Vaquero, N. Yahoo, J. Janzen, I. Singh, C. Fan, M. Rau, M. Feuchtenberger, E. Schwaneck, S. Cockell, J. Wilson-Kanamori, P. Ramachandran, C. Kho, T.J. Kendall, A.-L. Leblond, S.J. Keppler, P. Bielecki, K. Steiger, M. Hofmann, K. Rippe, H. Zitzelsberger, A. Weber, N. Malek, T. Luedde, M. Vucur, H.G. Augustin, R. Flavell, O. Parnas, R. Rad, O. Pabst, N.C. Henderson, S. Huber, A. Macpherson, P. Knolle, M. Claassen, A. Geier, C. Trautwein, K. Unger, E. Elinav, A. Waisman, Z. Abdullah, D. Haller, F. Tacke, Q.M. Anstee, M. Heikenwalder

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

95 Citations (Scopus)

Original language	English
Journal	Journal of Hepatology
DOIs	https://doi.org/10.1016/j.jhep.2023.04.037
Publication status	Published - 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.jhep.2023.04.037

Cite this

Kotsiliti, E., Leone, V., Schuehle, S., Govaere, O., Li, H., Wolf, M. J., Horvatic, H., Bierwirth, S., Hundertmark, J., Inverso, D., Zizmare, L., Sarusi-Portuguez, A., Gupta, R., O'Connor, T., Giannou, A. D., Shiri, A. M., Schlesinger, Y., Beccaria, M. G., Rennert, C., ... Heikenwalder, M. (2023). Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling. Journal of Hepatology. https://doi.org/10.1016/j.jhep.2023.04.037

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title = "Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling",

author = "E. Kotsiliti and V. Leone and S. Schuehle and O. Govaere and H. Li and M.J. Wolf and H. Horvatic and S. Bierwirth and J. Hundertmark and D. Inverso and L. Zizmare and A. Sarusi-Portuguez and R. Gupta and T. O'Connor and A.D. Giannou and A.M. Shiri and Y. Schlesinger and M.G. Beccaria and C. Rennert and D. Pfister and R. {\"O}llinger and I. Gadjalova and P. Ramadori and M. Rahbari and N. Rahbari and M.E. Healy and M. Fern{\'a}ndez-Vaquero and N. Yahoo and J. Janzen and I. Singh and C. Fan and M. Rau and M. Feuchtenberger and E. Schwaneck and S. Cockell and J. Wilson-Kanamori and P. Ramachandran and C. Kho and T.J. Kendall and A.-L. Leblond and S.J. Keppler and P. Bielecki and K. Steiger and M. Hofmann and K. Rippe and H. Zitzelsberger and A. Weber and N. Malek and T. Luedde and M. Vucur and H.G. Augustin and R. Flavell and O. Parnas and R. Rad and O. Pabst and N.C. Henderson and S. Huber and A. Macpherson and P. Knolle and M. Claassen and A. Geier and C. Trautwein and K. Unger and E. Elinav and A. Waisman and Z. Abdullah and D. Haller and F. Tacke and Q.M. Anstee and M. Heikenwalder",

year = "2023",

doi = "10.1016/j.jhep.2023.04.037",

language = "English",

journal = "Journal of Hepatology",

issn = "1600-0641",

}

Kotsiliti, E, Leone, V, Schuehle, S, Govaere, O, Li, H, Wolf, MJ, Horvatic, H, Bierwirth, S, Hundertmark, J, Inverso, D, Zizmare, L, Sarusi-Portuguez, A, Gupta, R, O'Connor, T, Giannou, AD, Shiri, AM, Schlesinger, Y, Beccaria, MG, Rennert, C, Pfister, D, Öllinger, R, Gadjalova, I, Ramadori, P, Rahbari, M, Rahbari, N, Healy, ME, Fernández-Vaquero, M, Yahoo, N, Janzen, J, Singh, I, Fan, C, Rau, M, Feuchtenberger, M, Schwaneck, E, Cockell, S, Wilson-Kanamori, J, Ramachandran, P, Kho, C, Kendall, TJ, Leblond, A-L, Keppler, SJ, Bielecki, P, Steiger, K, Hofmann, M, Rippe, K, Zitzelsberger, H, Weber, A, Malek, N, Luedde, T, Vucur, M, Augustin, HG, Flavell, R, Parnas, O, Rad, R, Pabst, O, Henderson, NC, Huber, S, Macpherson, A, Knolle, P, Claassen, M, Geier, A, Trautwein, C, Unger, K, Elinav, E, Waisman, A, Abdullah, Z, Haller, D, Tacke, F, Anstee, QM & Heikenwalder, M 2023, 'Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling', Journal of Hepatology. https://doi.org/10.1016/j.jhep.2023.04.037

TY - JOUR

T1 - Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

AU - Kotsiliti, E.

AU - Leone, V.

AU - Schuehle, S.

AU - Govaere, O.

AU - Li, H.

AU - Wolf, M.J.

AU - Horvatic, H.

AU - Bierwirth, S.

AU - Hundertmark, J.

AU - Inverso, D.

AU - Zizmare, L.

AU - Sarusi-Portuguez, A.

AU - Gupta, R.

AU - O'Connor, T.

AU - Giannou, A.D.

AU - Shiri, A.M.

AU - Schlesinger, Y.

AU - Beccaria, M.G.

AU - Rennert, C.

AU - Pfister, D.

AU - Öllinger, R.

AU - Gadjalova, I.

AU - Ramadori, P.

AU - Rahbari, M.

AU - Rahbari, N.

AU - Healy, M.E.

AU - Fernández-Vaquero, M.

AU - Yahoo, N.

AU - Janzen, J.

AU - Singh, I.

AU - Fan, C.

AU - Rau, M.

AU - Feuchtenberger, M.

AU - Schwaneck, E.

AU - Cockell, S.

AU - Wilson-Kanamori, J.

AU - Ramachandran, P.

AU - Kho, C.

AU - Kendall, T.J.

AU - Leblond, A.-L.

AU - Keppler, S.J.

AU - Bielecki, P.

AU - Steiger, K.

AU - Hofmann, M.

AU - Rippe, K.

AU - Zitzelsberger, H.

AU - Weber, A.

AU - Malek, N.

AU - Luedde, T.

AU - Vucur, M.

AU - Augustin, H.G.

AU - Flavell, R.

AU - Parnas, O.

AU - Rad, R.

AU - Pabst, O.

AU - Henderson, N.C.

AU - Huber, S.

AU - Macpherson, A.

AU - Knolle, P.

AU - Claassen, M.

AU - Geier, A.

AU - Trautwein, C.

AU - Unger, K.

AU - Elinav, E.

AU - Waisman, A.

AU - Abdullah, Z.

AU - Haller, D.

AU - Tacke, F.

AU - Anstee, Q.M.

AU - Heikenwalder, M.

PY - 2023

Y1 - 2023

UR - https://www.scopus.com/inward/record.url?eid=2-s2.0-85163564325&partnerID=MN8TOARS

U2 - 10.1016/j.jhep.2023.04.037

DO - 10.1016/j.jhep.2023.04.037

M3 - Article

SN - 1600-0641

JO - Journal of Hepatology

JF - Journal of Hepatology

ER -

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

UN SDGs

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