Interpreting streptomycin susceptibility test results for Salmonella enterica serovar Typhimurium

Geraldine Doran; Martina NiChulain; Niall DeLappe; Colette O'Hare; Geraldine Corbett-Feeney; Martin Cormican

doi:10.1016/j.ijantimicag.2006.03.005

Interpreting streptomycin susceptibility test results for Salmonella enterica serovar Typhimurium

Geraldine Doran
, Martina NiChulain
, Niall DeLappe
, Colette O'Hare
, Geraldine Corbett-Feeney
, Martin Cormican

Bacteriology

Research output: Contribution to a Journal (Peer & Non Peer) › Article › peer-review

16 Citations (Scopus)

Abstract

Resistance or susceptibility of Salmonella enterica to streptomycin is widely used as an epidemiological marker. However, there is no clear consensus on the interpretation of streptomycin susceptibility test results. Comparison of results obtained with the Clinical and Laboratory Standards Institute (CLSI) disk diffusion method, the minimum inhibitory concentration (MIC) determined by Etest and streptomycin resistance genotype for 90 isolates of S. enterica serovar Typhimurium suggests that appropriate interpretive criteria for MIC results are susceptible at ≤8 mg/L and resistant at ≥16 mg/L. For CLSI disk diffusion, we propose susceptible at a zone diameter ≥13 mm and resistant at ≤10 mm.

Original language	English
Pages (from-to)	538-540
Number of pages	3
Journal	International Journal of Antimicrobial Agents
Volume	27
Issue number	6
DOIs	https://doi.org/10.1016/j.ijantimicag.2006.03.005
Publication status	Published - 1 Jun 2006

Keywords

Disk diffusion
MIC
Resistance
Resistance genotype
Salmonella Typhimurium
Streptomycin

Authors (Note for portal: view the doc link for the full list of authors)

Authors
Doran, G;NiChulain, M;DeLappe, N;O'Hare, C;Corbett-Feeney, G;Cormican, M

Access to Document

10.1016/j.ijantimicag.2006.03.005

Cite this

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title = "Interpreting streptomycin susceptibility test results for Salmonella enterica serovar Typhimurium",

abstract = "Resistance or susceptibility of Salmonella enterica to streptomycin is widely used as an epidemiological marker. However, there is no clear consensus on the interpretation of streptomycin susceptibility test results. Comparison of results obtained with the Clinical and Laboratory Standards Institute (CLSI) disk diffusion method, the minimum inhibitory concentration (MIC) determined by Etest and streptomycin resistance genotype for 90 isolates of S. enterica serovar Typhimurium suggests that appropriate interpretive criteria for MIC results are susceptible at ≤8 mg/L and resistant at ≥16 mg/L. For CLSI disk diffusion, we propose susceptible at a zone diameter ≥13 mm and resistant at ≤10 mm.",

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year = "2006",

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TY - JOUR

T1 - Interpreting streptomycin susceptibility test results for Salmonella enterica serovar Typhimurium

AU - Doran, Geraldine

AU - NiChulain, Martina

AU - DeLappe, Niall

AU - O'Hare, Colette

AU - Corbett-Feeney, Geraldine

AU - Cormican, Martin

PY - 2006/6/1

Y1 - 2006/6/1

N2 - Resistance or susceptibility of Salmonella enterica to streptomycin is widely used as an epidemiological marker. However, there is no clear consensus on the interpretation of streptomycin susceptibility test results. Comparison of results obtained with the Clinical and Laboratory Standards Institute (CLSI) disk diffusion method, the minimum inhibitory concentration (MIC) determined by Etest and streptomycin resistance genotype for 90 isolates of S. enterica serovar Typhimurium suggests that appropriate interpretive criteria for MIC results are susceptible at ≤8 mg/L and resistant at ≥16 mg/L. For CLSI disk diffusion, we propose susceptible at a zone diameter ≥13 mm and resistant at ≤10 mm.

AB - Resistance or susceptibility of Salmonella enterica to streptomycin is widely used as an epidemiological marker. However, there is no clear consensus on the interpretation of streptomycin susceptibility test results. Comparison of results obtained with the Clinical and Laboratory Standards Institute (CLSI) disk diffusion method, the minimum inhibitory concentration (MIC) determined by Etest and streptomycin resistance genotype for 90 isolates of S. enterica serovar Typhimurium suggests that appropriate interpretive criteria for MIC results are susceptible at ≤8 mg/L and resistant at ≥16 mg/L. For CLSI disk diffusion, we propose susceptible at a zone diameter ≥13 mm and resistant at ≤10 mm.

KW - Disk diffusion

KW - MIC

KW - Resistance

KW - Resistance genotype

KW - Salmonella Typhimurium

KW - Streptomycin

UR - https://www.scopus.com/pages/publications/33747363181

U2 - 10.1016/j.ijantimicag.2006.03.005

DO - 10.1016/j.ijantimicag.2006.03.005

M3 - Article

SN - 0924-8579

VL - 27

SP - 538

EP - 540

JO - International Journal of Antimicrobial Agents

JF - International Journal of Antimicrobial Agents

IS - 6

ER -

Interpreting streptomycin susceptibility test results for Salmonella enterica serovar Typhimurium

Abstract

Keywords

Authors (Note for portal: view the doc link for the full list of authors)

Access to Document

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