TY - JOUR
T1 - Intentional and unintentional non-adherence to medications following an acute coronary syndrome
T2 - A longitudinal study
AU - Molloy, Gerard J.
AU - Messerli-Bürgy, Nadine
AU - Hutton, Gemma
AU - Wikman, Anna
AU - Perkins-Porras, Linda
AU - Steptoe, Andrew
PY - 2014/5
Y1 - 2014/5
N2 - Objective: Non-adherence to medication is common among coronary heart disease patients. Non-adherence to medication may be either intentional or unintentional. In this analysis we provide estimates of intentional and unintentional non-adherence in the year following an acute coronary syndrome (ACS). Method: In this descriptive prospective observational study of patients with confirmed ACS medication adherence measures were derived from responses to the Medication Adherence Report Scale at approximately 2. weeks (n. = 223), 6. months (n. = 139) and 12. months (n. = 136) following discharge from acute treatment for ACS. Results: Total medication non-adherence was 20%, 54% and 53% at each of these time points respectively. The corresponding figures for intentional non-adherence were 8%, 15% and 15% and 15%, 52% and 53% for unintentional non-adherence. There were significant increases in the levels of medication non-adherence between the immediate discharge period (2. weeks) and 6. months that appeared to stabilize between 6 and 12. months after acute treatment for ACS. Conclusion: Unintentional non-adherence to medications may be the primary form of non-adherence in the year following ACS. Interventions delivered early in the post-discharge period may prevent the relatively high levels of non-adherence that appear to become established by 6. months following an ACS.
AB - Objective: Non-adherence to medication is common among coronary heart disease patients. Non-adherence to medication may be either intentional or unintentional. In this analysis we provide estimates of intentional and unintentional non-adherence in the year following an acute coronary syndrome (ACS). Method: In this descriptive prospective observational study of patients with confirmed ACS medication adherence measures were derived from responses to the Medication Adherence Report Scale at approximately 2. weeks (n. = 223), 6. months (n. = 139) and 12. months (n. = 136) following discharge from acute treatment for ACS. Results: Total medication non-adherence was 20%, 54% and 53% at each of these time points respectively. The corresponding figures for intentional non-adherence were 8%, 15% and 15% and 15%, 52% and 53% for unintentional non-adherence. There were significant increases in the levels of medication non-adherence between the immediate discharge period (2. weeks) and 6. months that appeared to stabilize between 6 and 12. months after acute treatment for ACS. Conclusion: Unintentional non-adherence to medications may be the primary form of non-adherence in the year following ACS. Interventions delivered early in the post-discharge period may prevent the relatively high levels of non-adherence that appear to become established by 6. months following an ACS.
KW - Acute coronary syndrome
KW - Adherence
KW - Intention
KW - Psychological
UR - https://www.scopus.com/pages/publications/84898783075
U2 - 10.1016/j.jpsychores.2014.02.007
DO - 10.1016/j.jpsychores.2014.02.007
M3 - Article
SN - 0022-3999
VL - 76
SP - 430
EP - 432
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
IS - 5
ER -
